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Dipyridamole-lnduced Myocardial Ischemia
Theodore N. Keltz, MD;
Michael Innerfield, MD;
Bernard Gitler, MD;
Jerome A. Cooper, MD
JAMA. 1987;257(11):1515-1516.
Abstract
Angina and ischemic electrocardiographic changes occurred after administration of oral dipyridamole in four patients awaiting urgent myocardial revascularization procedures. To our knowledge, this has not previously been reported as a side effect of preoperative dipyridamole therapy, although dipyridamole-induced myocardial ischemia has been demonstrated to occur in animals and humans with coronary artery disease. Epicardial coronary collateral vessels were demonstrated in all four patients; a coronary "steal" phenomenon may be the mechanism of the dipyridamole-induced ischemia observed.
(JAMA 1987;257:1516-1517)
Author Affiliations
From the Division of Cardiology, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY.
Footnotes
Reprint requests to 150 Lockwood Ave, New Rochelle, NY 10801 (Dr Keltz).
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