 |
|
Massive Outbreak of Antimicrobial-Resistant Salmonellosis Traced to Pasteurized Milk
Caroline A. Ryan, MD;
Mary K. Nickels, MS;
Nancy T. Hargrett-Bean, PhD;
Morris E. Potter, DVM;
Tomy Endo, DrPH;
Leonard Mayer, PhD;
Carl W. Langkop, MSPH;
Carol Gibson;
Robert C. McDonald, MD;
Richard T. Kenney, MD;
Nancy D. Puhr;
Paul J. McDonnell;
Russell J. Martin, DVM, MPH;
Mitchell L. Cohen, MD;
Paul A. Blake, MD, MPH
JAMA. 1987;258(22):3269-3274.
Abstract
Two waves of antimicrobial-resistant Salmonella typhimurium infections in Illinois totaling over 16000 culture-confirmed cases were traced to two brands of pasteurized 2% milk produced by a single dairy plant. Salmonellosis was associated with taking antimicrobials before onset of illness. Two surveys to determine the number of persons who were actually affected yielded estimates of 168791 and 197581 persons, making this the largest outbreak of salmonellosis ever identified in the United States. The epidemic strain was easily identified because it had a rare antimicrobial resistance pattern and a highly unusual plasmid profile; study of stored isolates showed it had caused clusters of salmonellosis during the previous ten months that may have been related to the same plant, suggesting that the strain had persisted in the plant and repeatedly contaminated milk after pasteurization.
(JAMA 1987;258:3269-3274)
Author Affiliations
From the Division of Bacterial Diseases, Center for Infectious Diseases, Centers for Disease Control, Atlanta (Drs Ryan, Hargrett-Bean, Potter, Mayer, McDonald, Kenney, Cohen, and Blake and Ms Puhr), and the Illinois Department of Public Health, Springfield, III (Mss Nickels and Gibson, Drs Endo and Martin, and Messrs Langkop and McDonnell).
Footnotes
Reprint requests to Enteric Diseases Branch 1-5428, Division of Bacterial Diseases, Centers for Disease Control, Atlanta, GA 30333 (Dr Ryan).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati
What's this?
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Bacteriophages Reduce Experimental Contamination of Hard Surfaces, Tomato, Spinach, Broccoli, and Ground Beef by Escherichia coli O157:H7
Abuladze et al.
Appl. Environ. Microbiol. 2008;74:6230-6238.
ABSTRACT
| FULL TEXT
Botulism: Cause, Effects, Diagnosis, Clinical and Laboratory Identification, and Treatment Modalities
Dembek et al.
dmphp 2007;1:122-134.
ABSTRACT
| FULL TEXT
Opinions and practices of wisconsin dairy producers about biosecurity and animal well-being.
Hoe and Ruegg
J DAIRY SCI 2006;89:2297-2308.
ABSTRACT
| FULL TEXT
Prophylactic Antimicrobial Agents and the Importance of Fitness
Baden
NEJM 2005;353:1052-1054.
FULL TEXT
Biofilm Formation by Salmonella enterica Serovar Typhimurium and Escherichia coli on Epithelial Cells following Mixed Inoculations
Esteves et al.
Infect. Immun. 2005;73:5198-5203.
ABSTRACT
| FULL TEXT
Analyzing a bioterror attack on the food supply: The case of botulinum toxin in milk
Wein and Liu
Proc. Natl. Acad. Sci. USA 2005;102:9984-9989.
ABSTRACT
| FULL TEXT
Risk Factors for Development of Nontyphoid Salmonella Bacteremia
Grisaru-Soen et al.
CLIN PEDIATR 2004;43:825-829.
ABSTRACT
Acute Infectious Diarrhea
Marignani et al.
NEJM 2004;350:1576-1577.
FULL TEXT
Practical Food Safety Interventions for Dairy Production
Ruegg
J DAIRY SCI 2003;86:E1-9.
ABSTRACT
| FULL TEXT
Short and long term mortality associated with foodborne bacterial gastrointestinal infections: registry based study * Commentary: matched cohorts can be useful
Helms et al.
BMJ 2003;326:357-357.
ABSTRACT
| FULL TEXT
Molecular Basis of the Interaction of Salmonella with the Intestinal Mucosa
Darwin and Miller
Clin. Microbiol. Rev. 1999;12:405-428.
ABSTRACT
| FULL TEXT
Typhoid Fever
Zenilman
JAMA 1997;278:847-850.
ABSTRACT
Outbreak of Salmonella enteritidis Associated With Nationally Distributed Ice Cream Products-- Minnesota, South Dakota, and Wisconsin, 1994
JAMA 1994;272:1492-1494.
Update -- Listeriosis and Pasteurized Milk
JAMA 1989;261:1119-1119.
|
