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Council on Scientific Affairs; Positron Emission Tomography Panel; George M. Bohigian, MD; E. Harvey Estes, Jr, MD; Ira R Friedlander, MD; William R. Kennedy, MD; John H. Moxley III, MD; Patricia J. Numann, MD; Paul S. Salva; William C. Scott, MD; Joseph H. Skom, MD; Richard M. Steinhilber, MD; Jack P. Strong, MD; Henry N. Wagner, Jr, MD; William R. Hendee, PhD; William T. McGivney, PhD; Joanna S. Fowler, PhD; Edward J. Hoffman, PhD; Steven M. Larson, MD; Heinrich R. Schelbert, MD; Markus Schwaiger, MD; Henry N. Wagner, Jr, MD; Alfred P. Wolf, PhD; William R. Hendee, PhD

JAMA. 1988;259(12):1854-1860.

Abstract
Positron emission tomography (PET) can probe biochemical pathways in vivo and can provide quantitative data; for that purpose, tracers labeled with positron-emitting radioisotopes are essential. This report describes the tracers that are being used or that may have future use, their production by cyclotrons, and other needed resources for PET imaging. Current routine and automated methods for convenient production of labeled compounds, coupled with simple computer-controlled accelerators, can support the creation of clinical PET centers in any large medical institution, obviating the need for in-depth research teams. An alternate approach involves the development of regional centers that provide in-house service and that supply fluorine 18— and carbon 11—labeled compounds to nearby hospitals with PET machines.

(JAMA 1988;259:1854-1860)

Author Affiliations
St Louis, Chairman; Durham, NC; Chicago, Resident; Minneapolis; Los Angeles, Immediate Past Chairman; Syracuse, NY; Lubbock, Tex, Medical Student; Tucson, Vice-Chairman; Chicago; Cleveland; New Orleans; Baltimore; Secretary; Assistant Secretary; Upton, NY; Los Angeles; Bethesda, Md; Los Angeles; Los Angeles; Baltimore, Council Liaison; Upton, NY; Panel Secretary

From the Council on Scientific Affairs, American Medical Association, Chicago.

Footnotes
This report was presented to the House of Delegates of the American Medical Association at the 1987 Annual Meeting as an informational report.

This report is not intended to be construed or to serve as a standard of medical care. Standards of medical care are determined on the basis of all of the facts and circumstances involved in an individual case and are subject to change as scientific knowledge and technology advance and patterns of practice evolve. This report reflects the views of scientific literature as of February 1987.

Reprint requests to the Council on Scientific Affairs, American Medical Association, 535 N Dearborn St, Chicago, IL 60610 (William R. Hendee, PhD).

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