Experience with single-lung transplantation for pulmonary fibrosis. The Toronto Lung Transplant Group

Repeated success has now been obtained with single-lung transplantation for end-stage pulmonary fibrosis. Potential candidates for this procedure are individuals who are less than 60 years of age and who have progressive pulmonary deterioration with limited life expectancy. Since November 1983, eleven such transplantations have been performed; nine patients achieved discharge from the hospital and eight patients have remained alive up to 44 months after surgery. All of these recipients have good oxygenation on room air and good exercise tolerance and are capable of performing routine activities, including a return to previous employment. From our experience, it appears likely that single-lung transplantation can achieve the same success rates as other major organ transplantations.

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Retrograde flush following topical cooling is superior to preserve the non-heart-beating donor lung
Van De Wauwer et al.
Eur. J. Cardiothorac. Surg. 2007;31:1125-1133.
ABSTRACT | FULL TEXT  

In-situ topical cooling of lung grafts: early graft function and surfactant analysis in a porcine single lung transplant model
Kutschka et al.
Eur. J. Cardiothorac. Surg. 2003;24:411-419.
ABSTRACT | FULL TEXT  

Ischemia-Reperfusion-induced Lung Injury
de Perrot et al.
Am. J. Respir. Crit. Care Med. 2003;167:490-511.
ABSTRACT | FULL TEXT  

Bilateral versus single lung transplantation for chronic obstructive pulmonary disease: intermediate-term results
Pochettino et al.
Ann. Thorac. Surg. 2000;70:1813-1819.
ABSTRACT | FULL TEXT  

The relationship of ischemia-reperfusion injury of transplanted lung and the up-regulation of major histocompatibility complex II on host peripheral
Qayumi et al.
J. Thorac. Cardiovasc. Surg. 1998;115:978-982.
ABSTRACT | FULL TEXT  

Successful Transplantation of Lungs Topically Cooled in the Non-Heart-Beating Donor for 6 Hours
Steen et al.
Ann. Thorac. Surg. 1997;63:345-351.
ABSTRACT | FULL TEXT  

LIVING-DONOR LOBAR LUNG TRANSPLANTATION EXPERIENCE: INTERMEDIATE RESULTS
Starnes et al.
J. Thorac. Cardiovasc. Surg. 1996;112:1284-1291.
ABSTRACT | FULL TEXT  

Revascularization of the Bronchial Arteries in Lung Transplantation: An Overview
Norgaard et al.
Ann. Thorac. Surg. 1996;62:1215-1221.
ABSTRACT | FULL TEXT  

Unilateral Volume Reduction After Single-Lung Transplantation for Emphysema
Kroshus et al.
Ann. Thorac. Surg. 1996;62:363-368.
ABSTRACT | FULL TEXT  

Perfadex Is Superior to Euro-Collins Solution Regarding 24-Hour Preservation of Vascular Function
Ingemansson et al.
Ann. Thorac. Surg. 1995;60:1210-1214.
ABSTRACT | FULL TEXT  

Lobar transplantation: Indications, technique, and outcome
Starnes et al.
J. Thorac. Cardiovasc. Surg. 1994;108:403-411.
ABSTRACT | FULL TEXT  

Lung Transplantation: Samuel Jason Mixter Lecture
Pearson
Arch Surg 1989;124:535-538.
ABSTRACT  

The Politics of Organ Transplantation: A Parable of Our Time
Rettig
Journal of Health Politics, Policy and Law 1989;14:191-227.
ABSTRACT  

TRANSPLANTATION OF A SINGLE LUNG FOR PULMONARY FIBROSIS
JWatch General 1988;1988:7-7.
FULL TEXT