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A Case Report

Timothy James Pritchard, MD; Dan Arie Pankowsky, MD; Joseph Patrick Crowe, MD; Fadi William Abdul-Karim, MD

JAMA. 1988;259(15):2278-2280.

Abstract
The clinicopathological findings in a patient who developed breast carcinoma ten years after male-to-female sexual reassignment are reported. Only two other cases of transsexual men with breast carcinoma have been reported previously. All three patients received oral estrogens for prolonged periods to maintain secondary female characteristics. The controversies relating to hormonal influences in the etiology of breast cancer in men are discussed herein.

(JAMA 1988;259:-2278-2280)

Author Affiliations
From the Departments of Surgery (Drs Pritchard and Crowe) and Pathology (Drs Pankowsky and Abdul-Karim), University Hospitals of Cleveland.

Footnotes
Reprint requests to Department of Pathology, University Hospitals of Cleveland, 2085 Adelbert Rd, Cleveland, OH 44106 (Dr Abdul-Karim).

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