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Council on Scientific Affairs

JAMA. 1988;260(7):959-966.

Abstract
This report discusses some of the inherent limitations of cancer studies in animals and humans and presents a qualitative carcinogen risk assessment of a number of pesticides based on the judgment of national and international authorities who have reviewed the available experimental and epidemiologic evidence. A large number of pesticidal compounds have shown evidence of genotoxicity or carcinogenicity in animal and in vitro screening tests, but no pesticides—except arsenic and vinyl chloride (once used as an aerosol propellant)—definitely have been proved to be carcinogenic in man. Resolution 94 (1-86), which was referred to the Board of Trustees, calls for the American Medical Association, through its scientific journals and publications, to alert physicians to the potential hazards of agricultural pesticides, to provide physicians with advice on such hazards for their patients, and to urge that these substances be appropriately labeled. This report addresses the potential carcinogenicity of pesticides by review of the available literature.

(JAMA 1988;260:959-966)

Author Affiliations
From the Council on Scientific Affairs, American Medical Association, Chicago.

Footnotes
This report was presented to the AMA House of Delegates at the 1987 Interim Meeting as Council on Scientific Affairs Report B. The action of this report was adopted as amended.

This report is not intended to be construed or to serve as a standard of medical care. Standards of medical care are determined on the basis of all of the facts and circumstances involved in an individual case and are subject to change as scientific knowledge and technology advance and patterns of practice evolve. This report reflects the views of scientific literature as of December 1987.

Reprint requests to Council on Scientific Affairs, American Medical Association, 535 N Dearborn St, Chicago, IL60610 (William R. Hendee, PhD).

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