Serum 2,3,7,8-tetrachlorodibenzo-p-dioxin levels in US Army Vietnam-era veterans. The Centers for Disease Control Veterans Health Studies
This study investigates whether military records can be used to identify US
Army Vietnam veterans who were likely to be exposed to the herbicide Agent
Orange. Serum levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), a toxic
contaminant in Agent Orange, were obtained for 646 ground combat troops who
served in heavily sprayed areas of Vietnam and for 97 veterans who did not
serve in Vietnam. The distributions of current TCDD levels in Vietnam and
non-Vietnam veterans were nearly identical (mean in each group,
approximately equal to 4 parts per trillion [ppt]). Only two men (both
Vietnam veterans) had clearly elevated levels (greater than 20 ppt). Levels
of TCDD did not tend to increase with greater likelihood of exposure to
Agent Orange, as estimated from either military records or self-reported
exposure. This study is consistent with other studies and suggests that
most US Army ground troops who served in Vietnam were not heavily exposed
to TCDD, except perhaps men whose jobs involved handling herbicides.
