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Pregnancy-Associated Deaths due to AIDS in the United States
Lisa M. Koonin, MN, MPH;
Tedd V. Ellerbrock, MD;
Hani K. Atrash, MD, MPH;
Martha F. Rogers, MD;
Jack C. Smith, MS;
Carol J. R. Hogue, PhD, MPH;
Machelle A. Harris, MD;
Wendy Chavkin, MD, MPH;
Artist L. Parker, MD, MPH;
George J. Halpin, MD, MPH
JAMA. 1989;261(9):1306-1309.
Abstract
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From 1981 to 1988, eighty percent of all women with the acquired immunodeficiency syndrome (AIDS) reported to the Centers for Disease Control were of reproductive age. Six pregnancy-associated deaths due to AIDS in this country have been reported in the medical literature. We identified 20 unpublished cases of women who died of AIDS during or within one year after termination of pregnancy. Analysis showed that these women were mostly black or Hispanic, half were intravenous drug abusers, and most died of Pneumocystis carinii pneumonia. Each pregnancy had an obstetric complication, primarily preterm delivery. The interval between diagnosis of AIDS and the death of these women ranged from one day to 15 months, with a mean interval of 113 days. Multiple reporting sources increased case detection and should be used for future investigations. Prospective case-control studies are needed to determine any further relationship between pregnancy complications and AIDS.
(JAMA 1989;261:1306-1309)
Author Affiliations
From the Division of Reproductive Health, Center for Chronic Disease Prevention and Health Promotion (Ms Koonin, Drs Ellerbrock, Atrash, and Hogue, and Mr Smith), and the AIDS Program, Center for Infectious Diseases (Drs Ellerbrock and Rogers), Centers for Disease Control, Atlanta; the New York City Department of Health, Bureau of Maternity Services and Family Planning (Drs Harris and Chavkin); and the New Jersey Department of Health, Maternal and Child Health Services (Drs Parker and Halpin), Trenton.
Footnotes
Reprint requests to the Division of Reproductive Health, Centers for Disease Control, Mailstop C-06, 1600 Clifton Rd, Atlanta, GA 30333 (Ms Koonin).
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