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James R. Cooper, MD

JAMA. 1989;262(12):1664-1668.

Abstract
In light of the recent growth in public financial support for the rapid expansion of drug abuse treatment capacity, the unique effectiveness of methadone hydrochloride treatment in reducing intravenous opioid abuse and the associated sharing of injection equipment is reviewed and discussed, and its potential effect on preventing the spread of acquired immunodeficiency syndrome is examined. In addition to methadone, treatment variables that clinical research suggests are integral to effective treatment are identified. Methadone treatment is one of the most helpful means of reducing the risk of acquired immunodeficiency syndrome available, provided that programs of quality are expanded. The medical profession and universities are urged to take steps to ensure quality efforts in prevention and treatment.

(JAMA. 1989;262:1664-1668)

Author Affiliations
From the Office of Medical and International Affairs, National Institute on Drug Abuse, Rockville, Md.

Footnotes
Reprint requests to the Office of Medical and International Affairs, National Institute on Drug Abuse, Rockville, MD 20857 (Dr Cooper).

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