Rapid Eye Movement Sleep Behavior Disorder
Gugger and Wagner
The Annals of Pharmacotherapy 2007;41:1833-1841.
ABSTRACT
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Benzodiazepines and Hip Fractures
Wagner et al.
ANN INTERN MED 2007;147:348-348.
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A Drug Burden Index to Define the Functional Burden of Medications in Older People
Hilmer et al.
Arch Intern Med 2007;167:781-787.
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The Osteoporosis Self-Assessment Screening Tool: A Useful Tool for the Orthopaedic Surgeon
Skedros et al.
JBJS 2007;89:765-772.
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Effect of New York State Regulatory Action on Benzodiazepine Prescribing and Hip Fracture Rates
Wagner et al.
ANN INTERN MED 2007;146:96-103.
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Medication use as a risk factor for falls among hospitalized elderly patients
Walker et al.
Am J Health Syst Pharm 2005;62:2495-2499.
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Prevention of Fall-Related Injuries in Long-term Care: A Randomized Controlled Trial of Staff Education
Ray et al.
Arch Intern Med 2005;165:2293-2298.
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Statin Use and Fracture Risk: Study of a US Veterans Population
Scranton et al.
Arch Intern Med 2005;165:2007-2012.
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Efficacy and Tolerability of Citalopram in the Treatment of Late-Life Anxiety Disorders: Results From an 8-Week Randomized, Placebo-Controlled Trial
Lenze et al.
Am. J. Psychiatry 2005;162:146-150.
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Bias due to Aggregation of Individual Covariates in the Cox Regression Model
Abrahamowicz et al.
Am J Epidemiol 2004;160:696-706.
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Benzodiazepine Use and Hip Fractures in the Elderly: Who Is at Greatest Risk?
Wagner et al.
Arch Intern Med 2004;164:1567-1572.
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Reduced Mortality Associated With the Use of ACE Inhibitors in Patients With Type 2 Diabetes
Eurich et al.
Diabetes Care 2004;27:1330-1334.
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Aging Biology and Geriatric Clinical Pharmacology
McLean and Le Couteur
Pharmacol. Rev. 2004;56:163-184.
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Benzodiazepine Use and Risk of Mortality in Individuals Aged 85 Years or Older
Vinkers et al.
JAMA 2003;290:2942-2943.
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Evaluating Medication Effects Outside of Clinical Trials: New-User Designs
Ray
Am J Epidemiol 2003;158:915-920.
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Hypnotic Dependent Insomnia in an Older Adult with Addiction-Prone Personality
Cooper et al.
Clinical Case Studies 2003;2:247-258.
ABSTRACT
Effects of state surveillance on new post-hospitalization benzodiazepine use
Wagner et al.
Int J Qual Health Care 2003;15:423-431.
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Exposure to Tricyclic and Selective Serotonin Reuptake Inhibitor Antidepressants and the Risk of Hip Fracture
Hubbard et al.
Am J Epidemiol 2003;158:77-84.
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Central Nervous System Active Medications and Risk for Fractures in Older Women
Ensrud et al.
Arch Intern Med 2003;163:949-957.
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Educating physicians to reduce benzodiazepine use by elderly patients: a randomized controlled trial
Pimlott et al.
CMAJ 2003;168:835-839.
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Decreased Mortality Associated With the Use of Metformin Compared With Sulfonylurea Monotherapy in Type 2 Diabetes
Johnson et al.
Diabetes Care 2002;25:2244-2248.
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Sleep Problems in a Very Old Population: Drug Use and Clinical Correlates
Giron et al.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2002;57:M236-240.
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Benzodiazepines and hip fractures in elderly people: case-control study
Pierfitte et al.
BMJ 2001;322:704-708.
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Insomnia in the Context of Cancer: A Review of a Neglected Problem
Savard and Morin
JCO 2001;19:895-908.
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HMG-CoA Reductase Inhibitors and the Risk of Hip Fractures in Elderly Patients
Wang et al.
JAMA 2000;283:3211-3216.
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The diagnosis and management of insomnia in clinical practice: a practical evidence-based approach
Holbrook et al.
CMAJ 2000;162:216-210.
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Taking Policy Action to Reduce Benzodiazepine Use and Promote Self-Care Among Seniors
Hall
Journal of Applied Gerontology 1998;17:318-351.
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A Comparison of the Efficacy of Stimulus Control for Medicated and Nonmedicated Insomniacs
Riedel et al.
Behav Modif 1998;22:3-28.
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A Randomized Trial of a Consultation Service to Reduce Falls in Nursing Homes
Ray et al.
JAMA 1997;278:557-562.
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Benzodiazepine Use and the Risk of Motor Vehicle Crash in the Elderly
Hemmelgarn et al.
JAMA 1997;278:27-31.
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Safety and Mobility of the Older Driver: A Research Challenge
Ray
JAMA 1997;278:66-67.
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Characteristics of Physicians Who Frequently Prescribe Long-Acting Benzodiazepines for the Elderly
Moneyite et al.
Eval Health Prof 1997;20:115-130.
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Bertz et al.
J. Pharmacol. Exp. Ther. 1997;281:1317-1329.
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Addiction to Benzodiazepines-- How Common?
Grad
Arch Fam Med 1996;5:384-384.
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Hip Fracture
Zuckerman
NEJM 1996;334:1519-1525.
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Benzodiazepines and the Risk of Falling Leading to Femur Fractures: Dosage More Important Than Elimination Half-life
Herings et al.
Arch Intern Med 1995;155:1801-1807.
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Risk Factors for Hip Fracture in White Women
Cummings et al.
NEJM 1995;332:767-774.
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Benzodiazepine Utilization in a University Hospital
Zisselman et al.
American Journal of Medical Quality 1994;9:138-141.
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Inappropriate Drug Prescribing for the Community-Dwelling Elderly
Willcox et al.
JAMA 1994;272:292-296.
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Use of Benzodiazepines in the Community
Olfson and Pincus
Arch Intern Med 1994;154:1235-1240.
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Medications and Chronic Diseases as Risk Factors for Falling Injuries in the Elderly
Ryynanen et al.
Scand J Public Health 1993;21:264-271.
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Geriatric Medicine
Winograd and Gerety
JAMA 1993;270:213-216.
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Inappropriate Medication Prescribing in Skilled-Nursing Facilities
Beers et al.
ANN INTERN MED 1992;117:684-689.
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Adverse Behavioral Reactions Attributed to Triazolam in the Food and Drug Administration's Spontaneous Reporting System
Wysowski and Barash
Arch Intern Med 1991;151:2003-2008.
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Outpatient Use of Prescription Sedative-Hypnotic Drugs in the United States, 1970 Through 1989
Wysowski and Baum
Arch Intern Med 1991;151:1779-1783.
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The Ambiguous Relation between Aging and Adverse Drug Reactions
Gurwitz and Avorn
ANN INTERN MED 1991;114:956-966.
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Cyclic Antidepressants and the Risk of Hip Fracture
Ray and Griffin
Arch Intern Med 1991;151:754-756.
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Falls in Elderly Patients With Glaucoma
Glynn et al.
Arch Ophthalmol 1991;109:205-210.
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Pharmacodynamic Issues Relevant to Geriatric Psychopharmacology
Pollock et al.
J Geriatr Psychiatry Neurol 1990;3:221-228.
Benzodiazepines and Hip Fracture
Jacobs and Das
JAMA 1990;263:3260-3261.
ABSTRACT
LONG-ACTING BENZODIAZEPINES ASSOCIATED WITH HIP FRACTURE
JWatch General 1989;1989:3-3.
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24 hours) or short (<24 hours) elimination half-lives, we conducted a nested case-control study among residents of the Canadian province of Saskatchewan who were 65 years of age and older. We identified 4501 cases occurring between 1977 and 1985 from computerized hospital records and 24 041 population controls. Current benzodiazepine use, defined as having filled a prescription in the past 30 days, was ascertained from computerized pharmacy records. The relative risk of hip fracture was 1.7 (95% confidence interval, 1.5 to 2.0) for current users of long half-life benzodiazepines, in contrast to that of 1.1 (95% confidence interval, 0.9 to 1.3) for current users of short half-life drugs. This finding was not altered by sex, age, calendar year, nursing home residence, or history of hospitalization. Medical record review for a sample of 189 cases suggested that this finding was not due to confounding by dementia, ambulatory status, functional status, or body mass.