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Renee R. Lantner, MD; Baltazar R. Espiritu, MD; Patricia Zumerchik; Mary C. Tobin, MD

JAMA. 1990;264(19):2534-2536.

Abstract
Recently, psyllium hydrophilic mucilloid, a bulk-forming laxative, has been added to breakfast cereals for cholesterol-lowering effects. We report a case of a 60-year-old woman with no prior history of psyllium ingestion who developed anaphylactic symptoms after eating a psyllium-containing cereal. Her only previous exposure was dispensing a psyllium-containing laxative as a nurse. Immunoglobulin E—mediated sensitization was documented by skin testing and basophil histamine release. The literature is reviewed regarding allergic reactions to psyllium. Health care workers and pharmaceutical workers handling psyllium may be at increased risk due to sensitization from inhalation. Physicians and consumers should be aware of potential serious reactions from eating psyllium-containing cereals even without prior history of ingestion of psyllium.

(JAMA. 1990;264:2534-2536)

Author Affiliations
From the Section of Allergy/Immunology, Loyola University Stritch School of Medicine, Maywood, Ill.

Footnotes
Reprint requests to Allergy Section, Loyola University Medical Center, 2160 S First Ave, Bldg 117, Room 15, Maywood, IL 60153 (Dr Lantner).

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