The Development of Drug Metabolism Research as Expressed in the Publications of ASPET: Part 3, 1984-2008
Murphy
Drug Metab. Dispos. 2008;36:1977-1982.
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New Era in Drug Interaction Evaluation: US Food and Drug Administration Update on CYP Enzymes, Transporters, and the Guidance Process
Huang et al.
J Clin Pharmacol 2008;48:662-670.
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CYP2C19 Inhibition: The Impact of Substrate Probe Selection on in Vitro Inhibition Profiles
Foti and Wahlstrom
Drug Metab. Dispos. 2008;36:523-528.
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Effect of High-Dose Metronidazole on Pharmacokinetics of Oral Budesonide and Vice Versa: A Double Drug Interaction Study
Dilger et al.
J Clin Pharmacol 2007;47:1532-1539.
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On the relationship among QT interval, atrial fibrillation, and torsade de pointes
Roden et al.
Europace 2007;9:iv1-iv3.
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Detection and reporting of drug-induced proarrhythmias: room for improvement
Darpo
Europace 2007;9:iv23-iv36.
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Identification of Human Cytochrome P450 Isozymes Involved in Diphenhydramine N-Demethylation
Akutsu et al.
Drug Metab. Dispos. 2007;35:72-78.
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Torsades de Pointes Associated With Ziprasidone
Heinrich et al.
Psychosomatics 2006;47:264-268.
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Utility of hERG Assays as Surrogate Markers of Delayed Cardiac Repolarization and QT Safety
Gintant et al.
Toxicol Pathol 2006;34:81-90.
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Activation of Human ether-a-go-go-Related Gene Potassium Channels by the Diphenylurea 1,3-Bis-(2-hydroxy-5-trifluoromethyl-phenyl)-urea (NS1643)
Hansen et al.
Mol. Pharmacol. 2006;69:266-277.
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Treatment for Allergic Rhinitis and Chronic Idiopathic Urticaria: Focus on Oral Antihistamines
Morgan et al.
The Annals of Pharmacotherapy 2005;39:2056-2063.
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Pharmacogenomics of Tamoxifen in a Nutshell--And Who Broke the Nutcracker?
Holmes and Liticker
J Oncol Pract 2005;1:155-159.
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AUTOMATED SCREENING WITH CONFIRMATION OF MECHANISM-BASED INACTIVATION OF CYP3A4, CYP2C9, CYP2C19, CYP2D6, AND CYP1A2 IN POOLED HUMAN LIVER MICROSOMES
Lim et al.
Drug Metab. Dispos. 2005;33:1211-1219.
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The US Food and Drug Administration Cardiorenal Advisory Panel and the Drug Approval Process
Roden and Temple
Circulation 2005;111:1697-1702.
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An Underrecognized Challenge in Evaluating Postmarketing Drug Safety
Roden
Circulation 2005;111:246-248.
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DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
Williams et al.
Drug Metab. Dispos. 2004;32:1201-1208.
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Oral Erythromycin and the Risk of Sudden Death from Cardiac Causes
Ray et al.
NEJM 2004;351:1089-1096.
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Functional interaction between extracellular sodium, potassium and inactivation gating in HERG channels
Mullins et al.
J. Physiol. 2004;558:729-744.
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Drug-Induced Prolongation of the QT Interval
Roden
NEJM 2004;350:1013-1022.
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Electrophysiologic Properties and Antiarrhythmic Actions of a Novel Antianginal Agent
Antzelevitch et al.
J CARDIOVASC PHARMACOL THER 2004;9:S65-S83.
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Antihistamines
Armstrong and Cozza
Psychosomatics 2003;44:430-434.
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Use of OTC and Herbal Products in Patients with Cardiovascular Disease
Pharand et al.
The Annals of Pharmacotherapy 2003;37:899-904.
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Drug-Drug Interactions Among Elderly Patients Hospitalized for Drug Toxicity
Juurlink et al.
JAMA 2003;289:1652-1658.
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Extracellular Sodium Interacts with the HERG Channel at an Outer Pore Site
Mullins et al.
J. Gen. Physiol. 2002;120:517-537.
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Torsade de Pointes Associated with Very-High-Dose Methadone
Krantz et al.
ANN INTERN MED 2002;137:501-504.
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Spontaneous Adverse Event Reports of Serious Ventricular Arrhythmias, QT Prolongation, Syncope, and Sudden Death in Patients Treated with Cisapride
Barbey et al.
J CARDIOVASC PHARMACOL THER 2002;7:65-76.
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Antipsychotic Drugs: Prolonged QTc Interval, Torsade de Pointes, and Sudden Death
Glassman and Bigger
Am. J. Psychiatry 2001;158:1774-1782.
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Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes
Darpo
Eur Heart J Suppl 2001;3:K70-K80.
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Focus on issues in measuring and interpreting changes in the QTc interval duration
Morganroth
Eur Heart J Suppl 2001;3:K105-K111.
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Drug-induced torsade de pointes: the perspectives of industry
Barbey
Eur Heart J Suppl 2001;3:K112-K113.
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Evaluation of the Interaction of Loratadine and desloratadine with P-glycoprotein
Wang et al.
Drug Metab. Dispos. 2001;29:1080-1083.
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Suppression of Transient Outward Potassium Currents in Mouse Ventricular Myocytes by Imidazole Antimycotics and by Glybenclamide
Hernandez-Benito et al.
J. Pharmacol. Exp. Ther. 2001;298:598-606.
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Loratadine Blockade of K+ Channels in Human Heart: Comparison with Terfenadine under Physiological Conditions
Crumb
J. Pharmacol. Exp. Ther. 2000;292:261-264.
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Drug-drug interactions: How scared should we be?
Shapiro and Shear
CMAJ 1999;161:1266-1267.
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Impact of a Web-Based Clinical Information System on Cisapride Drug Interactions and Patient Safety
McMullin et al.
Arch Intern Med 1999;159:2077-2082.
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The pre-clinical assessment of QT interval prolongation: a comparison of in vitro and in vivo methods
Davis
Hum Exp Toxicol 1998;17:677-680.
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Blockage by Terfenadine of the Adenosine Triphosphate (ATP)-Sensitive K+ Current in Rabbit Ventricular Myocytes
Nishio et al.
J. Pharmacol. Exp. Ther. 1998;287:293-300.
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Prediction of Pharmacokinetic Alterations Caused by Drug-Drug Interactions: Metabolic Interaction in the Liver
Ito et al.
Pharmacol. Rev. 1998;50:387-412.
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Molecular Basis for the Lack of HERG K+ Channel Block-Related Cardiotoxicity by the H1 Receptor Blocker Cetirizine Compared with Other Second-Generation Antihistamines
Taglialatela et al.
Mol. Pharmacol. 1998;54:113-121.
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N-Dealkylation and Hydroxylation of Ebastine by Human Liver Cytochrome P450
Hashizume et al.
Drug Metab. Dispos. 1998;26:566-571.
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Proarrhythmia Associated With Cisapride in Children
Hill et al.
Pediatrics 1998;101:1053-1056.
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Role of Pharmacokinetics and Metabolism in Drug Discovery and Development
Lin and Lu
Pharmacol. Rev. 1997;49:403-449.
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Suppression of Mammalian K+ Channel Family by Ebastine
Ko et al.
J. Pharmacol. Exp. Ther. 1997;281:233-244.
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Of Oocytes and Runny Noses
Rosen
Circulation 1996;94:607-609.
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HERG, a Primary Human Ventricular Target of the Nonsedating Antihistamine Terfenadine
Roy et al.
Circulation 1996;94:817-823.
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Chronic Urticaria
Greaves
NEJM 1995;332:1767-1772.
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Regulation of Potassium Channels by Nonsedating Antihistamines
Berul and Morad
Circulation 1995;91:2220-2225.
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Cardiac Electrophysiological Actions of the Histamine H1-Receptor Antagonists Astemizole and Terfenadine Compared With Chlorpheniramine and Pyrilamine
Salata et al.
Circ. Res. 1995;76:110-119.
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Oral Azole Drugs as Systemic Antifungal Therapy
Como and Dismukes
NEJM 1994;330:263-272.
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POSSIBLE DANGEROUS INTERACTION BETWEEN TERFENADINE AND KETOCONAZOLE
JWatch General 1990;1990:1-1.
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