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Implications for Prevention Strategies

Eve M. Lackritz, MD; Hans O. Lobel, MD, MPH; B. Joann Howell; Peter Bloland, DVM, MPVM; Carlos C. Campbell, MD, MPH

JAMA. 1991;265(3):383-385.

Abstract
Data from the US National Malaria Surveillance System were analyzed to assess characteristics of travelers who acquired Plasmodium falciparum infections in Africa and evaluate the impact of chloroquine resistance on the incidence of imported malaria. Although the number of cases acquired in East Africa has stabilized, the number of imported P falciparum infections acquired in West Africa increased threefold from 1985 to 1988, and the proportion of travelers who reported failure of chloroquine prophylaxis increased from 10% to 48%. Fifty-eight percent of patients who acquired malaria in West Africa had not used chemoprophylaxis. To curb the rising incidence of P falciparum infections in American travelers, the Centers for Disease Control revised malaria prophylaxis recommendations to include the use of mefloquine in areas of chloroquine resistance. Use of malaria protection measures by travelers to West Africa must also be improved.

(JAMA. 1991;265:383-385)

Author Affiliations
From the Division of Parasitic Diseases, Center for Infectious Diseases, Centers for Disease Control, Public Health Service, US Department of Health and Human Services, Atlanta, Ga.

Footnotes
Reprint requests to Malaria Branch, Mailstop F-12, Centers for Disease Control, 1600 Clifton Rd, Atlanta, GA 30333 (Dr Lackritz).

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