A case-control study of baldness in relation to myocardial infarction in men
S. M. Lesko, L. Rosenberg and S. Shapiro
Slone Epidemiology Unit, Boston University School of Medicine, Brookline, Mass. 02146.
OBJECTIVE--To examine the relationship between male pattern baldness and
the risk of myocardial infarction in men under the age of 55 years. DESIGN
AND PARTICIPANTS--A hospital-based, case-control study was conducted in
eastern Massachusetts and Rhode Island. Cases were men admitted to a
hospital for a first nonfatal myocardial infarction (n = 665); controls
were men admitted to the same hospitals with noncardiac diagnoses (n =
772). Extent of baldness was assessed using the 12-point modified Hamilton
Baldness Scale; other information was obtained by personal interview. Among
the controls, the prevalence of any baldness was 34%, while the prevalence
of baldness involving the vertex scalp was 23%. RESULTS--After allowing for
age, the relative risk estimate for frontal baldness compared with no hair
loss was 0.9 (95% confidence interval, 0.6 to 1.3), for baldness involving
the vertex scalp it was 1.4 (95% confidence interval, 1.2 to 1.9). Risk of
myocardial infarction increased as the degree of vertex baldness increased
(P < .01); for severe vertex baldness the relative risk was 3.4 (95%
confidence interval, 1.7 to 7.0). The relationship between vertex baldness
and myocardial infarction was consistent within strata defined by age and
other risk factors for coronary artery disease. CONCLUSION--These data
support the hypothesis that male pattern baldness involving the vertex
scalp is associated with coronary artery disease in men under the age of 55
years.
Baldness and Myocardial Infarction in Men: The Atherosclerosis Risk in Communities Study
Shahar et al.
Am J Epidemiol 2008;167:676-683.
ABSTRACT
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Acne in Adolescence and Cause-specific Mortality: Lower Coronary Heart Disease but Higher Prostate Cancer Mortality: The Glasgow Alumni Cohort Study
Galobardes et al.
Am J Epidemiol 2005;161:1094-1101.
ABSTRACT
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Baldness and Coronary Artery Disease: The Dermatologic Point of View of a Controversial Issue
Rebora
Arch Dermatol 2001;137:943-947.
ABSTRACT
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Male Pattern Baldness and Clinical Prostate Cancer in the Epidemiologic Follow-Up of the First National Health and Nutrition Examination Survey
Hawk et al.
Cancer Epidemiol. Biomarkers Prev. 2000;9:523-527.
ABSTRACT
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Male Pattern Baldness and Coronary Heart Disease: The Physicians' Health Study
Lotufo et al.
Arch Intern Med 2000;160:165-171.
ABSTRACT
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Androgen Deprivation Is Associated With Enhanced Endothelium-Dependent Dilatation in Adult Men
Herman et al.
Arterioscler. Thromb. Vasc. Bio. 1997;17:2004-2009.
ABSTRACT
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Premature grey hair and hair loss among smokers: a new opportunity for health education?
Mosley and Gibbs
BMJ 1996;313:1616-1616.
FULL TEXT
Testosterone Increases Human Platelet Thromboxane A2 Receptor Density and Aggregation Responses
Ajayi et al.
Circulation 1995;91:2742-2747.
ABSTRACT
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Is Baldness a Predictor of Coronary Artery Disease in Men?
Journal Watch Dermatology 1993;1993:11-11.
FULL TEXT
VERTEX BALDNESS IS LINKED TO MI RISK
JWatch General 1993;1993:2-2.
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