Hyperhomocysteinemia and Lower Extremity Wounds
Schwartzfarb and Romanelli
INT J LOW EXTREM WOUNDS 2008;7:126-136.
ABSTRACT
Murine Models of Hyperhomocysteinemia and Their Vascular Phenotypes
Dayal and Lentz
Arterioscler. Thromb. Vasc. Bio. 2008;28:1596-1605.
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Folate Deficiency Induces Neurodegeneration and Brain Dysfunction in Mice Lacking Uracil DNA Glycosylase
Kronenberg et al.
J. Neurosci. 2008;28:7219-7230.
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Chronic diet-induced hyperhomocysteinemia impairs eNOS regulation in mouse mesenteric arteries
Looft-Wilson et al.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 2008;295:R59-R66.
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Plasma B Vitamins, Homocysteine, and Their Relation with Bone Loss and Hip Fracture in Elderly Men and Women
McLean et al.
J. Clin. Endocrinol. Metab. 2008;93:2206-2212.
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Association of Plasma Total Homocysteine Levels With Subclinical Brain Injury: Cerebral Volumes, White Matter Hyperintensity, and Silent Brain Infarcts at Volumetric Magnetic Resonance Imaging in the Framingham Offspring Study
Seshadri et al.
Arch Neurol 2008;65:642-649.
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Walking or vitamin B for cognition in older adults with mild cognitive impairment? A randomised controlled trial
van Uffelen et al.
Br. J. Sports. Med. 2008;42:344-351.
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Is folic acid good for everyone?
Smith et al.
Am. J. Clin. Nutr. 2008;87:517-533.
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Intake of Folate, Vitamin B6 and Vitamin B12 and the Risk of CHD: The Japan Public Health Center-Based Prospective Study Cohort I
Ishihara et al.
J. Am. Coll. Nutr. 2008;27:127-136.
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Homocysteine Levels in Epileptic Children Receiving Antiepileptic Drugs
Kurul et al.
J Child Neurol 2007;22:1389-1392.
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Homocysteine, vitamins, and vascular disease prevention
McCully
Am. J. Clin. Nutr. 2007;86:1563S-1568S.
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Trends in blood folate and vitamin B-12 concentrations in the United States, 1988 2004
Pfeiffer et al.
Am. J. Clin. Nutr. 2007;86:718-727.
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Effect of Folic Acid and Vitamins B6 and B12 on Microcirculatory Vasoreactivity in Patients With Hyperhomocysteinemia
Abularrage et al.
VASC ENDOVASCULAR SURG 2007;41:339-345.
ABSTRACT
Plasma vitamin B-6 forms and their relation to transsulfuration metabolites in a large, population-based study
Midttun et al.
Am. J. Clin. Nutr. 2007;86:131-138.
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The Homocysteine Hypothesis of Depression
Folstein et al.
Am. J. Psychiatry 2007;164:861-867.
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Correlations Between Folate, B12, Homocysteine Levels, and Radiological Markers of Neuropathology in Elderly Post-Stroke Patients
Yang et al.
J. Am. Coll. Nutr. 2007;26:272-278.
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Vitamin B-12 Deficiency Is Prevalent in 35- to 64-Year-Old Chinese Adults
Hao et al.
J. Nutr. 2007;137:1278-1285.
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Relationship of Homocysteine Levels to Quadriceps Strength, Gait Speed, and Late-Life Disability in Older Adults
Kuo et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2007;62:434-439.
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Multiple Biomarkers and the Risk of Incident Hypertension
Wang et al.
Hypertension 2007;49:432-438.
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Both vitamin B6 and total homocysteine plasma levels predict long-term atherothrombotic events in healthy subjects
Vanuzzo et al.
Eur Heart J 2007;28:484-491.
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Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial
Green et al.
Am. J. Clin. Nutr. 2007;85:460-464.
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Cardiovascular Fitness Is Negatively Associated With Homocysteine Levels in Female Adolescents
Ruiz et al.
Arch Pediatr Adolesc Med 2007;161:166-171.
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A Dietary Screening Questionnaire Identifies Dietary Patterns in Older Adults
Bailey et al.
J. Nutr. 2007;137:421-426.
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Effects of Folic Acid Supplementation on Hearing in Older Adults: A Randomized, Controlled Trial
Durga et al.
ANN INTERN MED 2007;146:1-9.
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Homocysteine Thiolactone-Induced Hyperhomocysteinemia Does Not Alter Concentrations of Cholesterol and SREBP-2 Target Gene mRNAs in Rats
Stangl et al.
Exp. Biol. Med. 2007;232:81-87.
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Effect of Folic Acid Supplementation on Risk of Cardiovascular Diseases: A Meta-analysis of Randomized Controlled Trials
Bazzano et al.
JAMA 2006;296:2720-2726.
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Serum sex hormone and plasma homocysteine levels in middle-aged and elderly men
Pour et al.
Eur J Endocrinol 2006;155:887-893.
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Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderly
Ravaglia et al.
Am. J. Clin. Nutr. 2006;84:1473-1480.
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Population reference values for plasma total homocysteine concentrations in US adults after the fortification of cereals with folic acid.
Ganji and Kafai
Am. J. Clin. Nutr. 2006;84:989-994.
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Global DNA and p53 Region-Specific Hypomethylation in Human Colonic Cells Is Induced by Folate Depletion and Reversed by Folate Supplementation
Wasson et al.
J. Nutr. 2006;136:2748-2753.
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Homocysteine Hypothesis for Atherothrombotic Cardiovascular Disease: Not Validated
Kaul et al.
J Am Coll Cardiol 2006;48:914-923.
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Plasma Total Homocysteine Levels in Children with Type 1 Diabetes: Relationship with Vitamin Status, Methylene Tetrahydrofolate Reductase Genotype, Disease Parameters and Coronary Risk Factors
Dinleyici et al.
J Trop Pediatr 2006;52:260-266.
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Dietary folate, vitamin B12, and vitamin B6 and the risk of Parkinson disease.
de Lau et al.
Neurology 2006;67:315-318.
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Choline Deficiency Is Associated With Increased Risk for Venous Catheter Thrombosis
Buchman et al.
JPEN J Parenter Enteral Nutr 2006;30:317-320.
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A controlled trial of homocysteine lowering and cognitive performance.
McMahon et al.
NEJM 2006;354:2764-2772.
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Primary Prevention of Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline.
Goldstein et al.
Circulation 2006;113:e873-e923.
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Serum homocysteine is related to food intake in adolescents: the Child and Adolescent Trial for Cardiovascular Health
Lutsey et al.
Am. J. Clin. Nutr. 2006;83:1380-1386.
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The Many Facets of Hyperhomocysteinemia: Studies from the Framingham Cohorts
Selhub
J. Nutr. 2006;136:1726S-1730S.
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The Hordaland Homocysteine Study: A Community-Based Study of Homocysteine, Its Determinants, and Associations with Disease
Refsum et al.
J. Nutr. 2006;136:1731S-1740S.
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Primary Prevention of Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline.
Goldstein et al.
Stroke 2006;37:1583-1633.
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Folate and human reproduction
Tamura and Picciano
Am. J. Clin. Nutr. 2006;83:993-1016.
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Food frequency questionnaires: not irrelevant yet.
Kelemen
Cancer Epidemiol. Biomarkers Prev. 2006;15:1054-1054.
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Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population
Devlin et al.
Am. J. Clin. Nutr. 2006;83:708-713.
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Folate, Vitamin B6, Multivitamin Supplements, and Colorectal Cancer Risk in Women
Zhang et al.
Am J Epidemiol 2006;163:108-115.
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Homocysteine Level and Coronary Artery Disease
Kazemi et al.
ANGIOLOGY 2006;57:9-14.
ABSTRACT
Genetic and Epigenetic Interactions between Folate and Aging in Carcinogenesis
Jang et al.
J. Nutr. 2005;135:2967S-2971S.
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Changes in Biological Markers of Health: Older Americans in the 1990s
Crimmins et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2005;60:1409-1413.
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Folate, But Not Homocysteine, Predicts the Risk of Fracture in Elderly Persons
Ravaglia et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2005;60:1458-1462.
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Dose-dependent effects of folic acid on blood concentrations of homocysteine: a meta-analysis of the randomized trials
Homocysteine Lowering Trialists' Collaboration
Am. J. Clin. Nutr. 2005;82:806-812.
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Homocysteine and folate as risk factors for dementia and Alzheimer disease
Ravaglia et al.
Am. J. Clin. Nutr. 2005;82:636-643.
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The Role of Homocysteine in Multisystem Age-Related Problems: A Systematic Review
Kuo et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2005;60:1190-1201.
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Population References for Plasma Total Homocysteine Concentrations for U.S. Children and Adolescents in the Post-Folic Acid Fortification Era
Ganji and Kafai
J. Nutr. 2005;135:2253-2256.
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Folate and Vitamin B12 for Hip Fracture Prevention After Stroke--Reply
Sato et al.
JAMA 2005;294:792-792.
FULL TEXT
Biochemical indicators of B vitamin status in the US population after folic acid fortification: results from the National Health and Nutrition Examination Survey 1999-2000
Pfeiffer et al.
Am. J. Clin. Nutr. 2005;82:442-450.
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A Homocysteine Metabolism-Related Dietary Pattern and the Risk of Coronary Heart Disease in Two Independent German Study Populations
Weikert et al.
J. Nutr. 2005;135:1981-1988.
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Homocysteine, Lipid Profile, Nitric Oxide, Vitamin B12, and Folate Values in Patients with Premature Coronary Artery Disease and Their Children
Pac et al.
ANGIOLOGY 2005;56:253-257.
ABSTRACT
The Methylenetetrahydrofolate Reductase 677C->T Polymorphism and Dietary Folate Restriction Affect Plasma One-Carbon Metabolites and Red Blood Cell Folate Concentrations and Distribution in Women
Davis et al.
J. Nutr. 2005;135:1040-1044.
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Homocysteine Synthesis Is Elevated but Total Remethylation Is Unchanged by the Methylenetetrahydrofolate Reductase 677C->T Polymorphism and by Dietary Folate Restriction in Young Women
Davis et al.
J. Nutr. 2005;135:1045-1050.
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Oral Estradiol Decreases Plasma Homocysteine, Vitamin B6, and Albumin in Postmenopausal Women But Does Not Change the Whole-Body Homocysteine Remethylation and Transmethylation Flux
Smolders et al.
J. Clin. Endocrinol. Metab. 2005;90:2218-2224.
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Dietary vitamin B-6 restriction does not alter rates of homocysteine remethylation or synthesis in healthy young women and men
Davis et al.
Am. J. Clin. Nutr. 2005;81:648-655.
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Folate Transport Gene Inactivation in Mice Increases Sensitivity to Colon Carcinogenesis
Ma et al.
Cancer Res. 2005;65:887-897.
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Effect of an Enriched Drink on Cognitive Function in Frail Elderly Persons
Wouters-Wesseling et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2005;60:265-270.
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Folate Intake and the Risk of Incident Hypertension Among US Women
Forman et al.
JAMA 2005;293:320-329.
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CDC/AHA Workshop on Markers of Inflammation and Cardiovascular Disease: Application to Clinical and Public Health Practice: Ability of Inflammatory Markers to Predict Disease in Asymptomatic Patients: A Background Paper
Wilson
Circulation 2004;110:e568-e571.
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Homocysteine and B Vitamins Relate to Brain Volume and White-Matter Changes in Geriatric Patients With Psychiatric Disorders
Scott et al.
AJGP 2004;12:631-638.
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Frequent consumption of milk, yogurt, cold breakfast cereals, peppers, and cruciferous vegetables and intakes of dietary folate and riboflavin but not vitamins B-12 and B-6 are inversely associated with serum total homocysteine concentrations in the US population
Ganji and Kafai
Am. J. Clin. Nutr. 2004;80:1500-1507.
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Homocysteine and cognitive function in elderly people
Garcia and Zanibbi
CMAJ 2004;171:897-904.
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Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention
Bleie et al.
Am. J. Clin. Nutr. 2004;80:641-648.
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Effect of folic acid on homocysteine-induced trophoblast apoptosis
Di Simone et al.
Mol Hum Reprod 2004;10:665-669.
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Folate Intake and Risk of Parkinson's Disease
Chen et al.
Am J Epidemiol 2004;160:368-375.
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Serum folate and homocysteine and the incidence of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study
Voutilainen et al.
Am. J. Clin. Nutr. 2004;80:317-323.
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Hyperhomocysteinemia, Low Folate and Vitamin B12 Concentrations, and Methylene Tetrahydrofolate Reductase Mutation in Cerebral Venous Thrombosis
Cantu et al.
Stroke 2004;35:1790-1794.
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Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, Alzheimer disease, and vascular dementia
Quadri et al.
Am. J. Clin. Nutr. 2004;80:114-122.
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A Prospective Study of Diet and Benign Breast Disease
Webb et al.
Cancer Epidemiol. Biomarkers Prev. 2004;13:1106-1113.
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Serum Selenium Is Associated with Plasma Homocysteine Concentrations in Elderly Humans
Gonzalez et al.
J. Nutr. 2004;134:1736-1740.
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Perturbations in homocysteine-linked redox homeostasis in a murine model for hyperhomocysteinemia
Vitvitsky et al.
Am. J. Physiol. Regul. Integr. Comp. Physiol. 2004;287:R39-R46.
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Communicating Cardiovascular Disease Risk Due to Elevated Homocysteine Levels: Using the EPPM to Develop Print Materials
McKay et al.
Health Educ Behav 2004;31:355-371.
ABSTRACT
Homocysteine as a Predictive Factor for Hip Fracture in Older Persons
McLean et al.
NEJM 2004;350:2042-2049.
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Breakfast cereal fortified with folic acid, vitamin B-6, and vitamin B-12 increases vitamin concentrations and reduces homocysteine concentrations: a randomized trial
Tucker et al.
Am. J. Clin. Nutr. 2004;79:805-811.
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Diet and risk of ischemic heart disease in India
Rastogi et al.
Am. J. Clin. Nutr. 2004;79:582-592.
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Folate and colorectal neoplasia: relation between plasma and dietary markers of folate and adenoma recurrence
Martinez et al.
Am. J. Clin. Nutr. 2004;79:691-697.
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Mild Hyperhomocysteinemia Induced by Feeding Rats Diets Rich in Methionine or Deficient in Folate Promotes Early Atherosclerotic Inflammatory Processes
Zhang et al.
J. Nutr. 2004;134:825-830.
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Plasma C-Reactive Protein and Homocysteine Concentrations Are Related to Frequent Fruit and Vegetable Intake in Hispanic and Non-Hispanic White Elders
Gao et al.
J. Nutr. 2004;134:913-918.
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Folate deprivation reduces homocysteine remethylation in a human intestinal epithelial cell culture model: role of serine in one-carbon donation
Townsend et al.
Am. J. Physiol. Gastrointest. Liver Physiol. 2004;286:G588-G595.
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Relations of plasma homocysteine to left ventricular structure and function: the Framingham Heart Study
Sundstrom et al.
Eur Heart J 2004;25:523-530.
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High-Level Multiplex Genotyping of Polymorphisms Involved in Folate or Homocysteine Metabolism by Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry
Meyer et al.
Clin. Chem. 2004;50:391-402.
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Genetic Determinants of Arterial Thrombosis
Voetsch and Loscalzo
Arterioscler. Thromb. Vasc. Bio. 2004;24:216-229.
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Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor
Davis et al.
Am. J. Physiol. Endocrinol. Metab. 2004;286:E272-E279.
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Facts and Recommendations about Total Homocysteine Determinations: An Expert Opinion
Refsum et al.
Clin. Chem. 2004;50:3-32.
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Hyperhomocysteinemia as an independent risk factor for silent brain infarction
Kim et al.
Neurology 2003;61:1595-1599.
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Age Dependence of the Influence of Methylenetetrahydrofolate Reductase Genotype on Plasma Homocysteine Level
Spotila et al.
Am J Epidemiol 2003;158:871-877.
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Age and Gender Affect the Relation between Methylenetetrahydrofolate Reductase C677T Genotype and Fasting Plasma Homocysteine Concentrations in the Framingham Offspring Study Cohort
Russo et al.
J. Nutr. 2003;133:3416-3421.
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Geographical, Seasonal and Gender Differences in Folate Status among Chinese Adults
Hao et al.
J. Nutr. 2003;133:3630-3635.
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Dietary Pattern Is Associated with Homocysteine and B Vitamin Status in an Urban Chinese Population
Gao et al.
J. Nutr. 2003;133:3636-3642.
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Joint Association of Alcohol and Folate Intake with Risk of Major Chronic Disease in Women
Jiang et al.
Am J Epidemiol 2003;158:760-771.
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B vitamin status and concentrations of homocysteine and methylmalonic acid in elderly German women
Wolters et al.
Am. J. Clin. Nutr. 2003;78:765-772.
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Complex Multivitamin Supplementation Improves Homocysteine and Resistance to LDL-C Oxidation
Earnest et al.
J. Am. Coll. Nutr. 2003;22:400-407.
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Homocysteine and cognitive function in the Sacramento Area Latino Study on Aging
Miller et al.
Am. J. Clin. Nutr. 2003;78:441-447.
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