Prevalence of hepatitis B markers and measles, mumps, and rubella antibodies among Jewish refugees from the former Soviet Union
M. B. Hurie, M. A. Gennis, L. V. Hernandez, V. J. Dindzans and J. P. Davis
Communicable Diseases Section, Bureau of Public Health, Madison, WI 53703-3044.
OBJECTIVE--To assess the prevalence of hepatitis B virus (HBV) infection
and immunity to measles, mumps, and rubella among refugees from the former
Soviet Union (FSU). DESIGN--Descriptive study. SETTING--Soviet Immigrant
Health Care Program, Sinai Samaritan Hospital, Milwaukee, Wis.
PATIENTS--Consecutive sample of 496 Jewish refugees from the FSU presenting
for new arrival screening from December 1, 1990, through January 11, 1993.
OUTCOME MEASURES--Hepatitis B surface antigen (HBsAg), hepatitis B core
antibody, hepatitis B surface antibody, and measles, mumps, and rubella
antibodies. RESULTS--At least one hepatitis B marker was detected in 22% of
the refugees, and HBsAg was detected in 0.4%. The rate of HBV infection
(any marker present) increased with increasing age, ranging from 4% among
those aged 0 through 19 years to 31% among those aged 50 through 59 years
(chi 2 test for trend, 13.5; P < .001). Among those aged 0 through 19
years, 19% lacked antibody to measles, 8% lacked antibody to mumps, and 13%
lacked antibody to rubella. Refugees who were less than 30 years of age
were more than twice as likely to lack antibodies to measles, mumps, or
rubella compared with those who were 30 years of age or older (relative
risk, 2.8; 95% confidence interval, 1.8 to 4.2; P < .001).
CONCLUSIONS--In our sample of Jewish refugees from the FSU (primarily
Ukraine, Russia, and Belorussia), the rate of HBsAg positivity was low,
suggesting that routine screening for HBV infection is not needed.
Seronegativity to measles, mumps, and rubella was relatively common among
those less than 30 years old. Those refugees who were born after 1957
should be given combined measles, mumps, and rubella vaccine unless their
written documentation indicates previous receipt of these antigens
according to the immunization schedule recommended in the United States.
