This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

Kevin M. De Cock, MD, FRCP, DTM&H; Nancy J. Binkin, MD, MPH; Patrick L. F. Zuber, MD, MPH; Jordan W. Tappero, MD, MPH; Kenneth G. Castro, MD

JAMA. 1996;276(18):1502-1507.

Abstract
Each year, there are an estimated 8 million new cases of tuberculosis (TB) and 3 million deaths due to TB, most of which occur in resource-poor countries. Tuberculosis incidence is increasing rapidly in countries with high rates of human immunodeficiency virus (HIV) infection, and despite the availability of effective interventions, many TB programs are failing to cope with the increased TB caseload. This report highlights gaps in current understanding of the interaction between TB and HIV that contribute to failure of optimal TB management and control; we focus on the diagnosis of TB, its epidemiology and transmission, preventive strategies, and programmatic issues in the integration of HIV and TB services. Research into how best to apply existing knowledge will be at least as important as searching for new knowledge. The global control of TB will also require increased resources, greater political commitment, and stronger international public health leadership.

Author Affiliations
From the London School of Hygiene and Tropical Medicine (Dr De Cock), London, United Kingdom; and the Division of Tuberculosis Elimination, National Center for HIV/STD/TB Prevention, Centers for Disease Control and Prevention, Atlanta, Ga (Drs Binkin, Zuber, Tappero, and Castro).

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Management of Tuberculosis in the United States
Small and Fujiwara
NEJM 2001;345:189-200.
FULL TEXT  

Global Burden of Tuberculosis: Estimated Incidence, Prevalence, and Mortality by Country
Dye et al.
JAMA 1999;282:677-686.
ABSTRACT | FULL TEXT  

Molecular Fingerprinting of Mycobacterium tuberculosis and Risk Factors for Tuberculosis Transmission in Paris, France, and Surrounding Area
Gutiérrez et al.
J. Clin. Microbiol. 1998;36:486-492.
ABSTRACT | FULL TEXT  

Tuberculosis Research: Balancing the Portfolio
Small
JAMA 1996;276:1512-1513.
ABSTRACT