You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT JAMA
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 277 No. 2, January 8, 1997 TABLE OF CONTENTS
  JAMA
  •  Online Features
  Original Contributions
 This Article
 •References
 •Full text PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Citation map
 •Citing articles on HighWire
 •Contact me when this article is cited
 Related Content
 •Similar articles in JAMA
 Social Bookmarking
  Add to CiteULike Add to Connotea Add to Del.icio.us Add to Digg Add to Reddit Add to Technorati
What's this?

Results at Age 8 Years of Early Intervention for Low-Birth-Weight Premature Infants

The Infant Health and Development Program

Cecelia M. McCarton, MD; Jeanne Brooks-Gunn, PhD; Ina F. Wallace, PhD; Charles R. Bauer, MD; Forrest C. Bennett, MD; Judy C. Bernbaum, MD; R. Sue Broyles, MD; Patrick H. Casey, MD; Marie C. McCormick, MD, ScD; David T. Scott, PhD; Jon Tyson, MD; James Tonasela, PhD; Curtis L. Meinen, PhD

JAMA. 1997;277(2):126-132.


Abstract

Objective.
—To reevaluate at age 8 years children who had participated during the first 3 years of life in a randomized clinical trial of special services for low-birthweight (LBW) premature infants.

Design.
—Follow-up of a randomized controlled trial of premature infants (<37 weeks' gestation), stratified by 2 LBW groups (lighter [<2000 g] and heavier [2001 2500 g]) and divided into intervention (n=377) and follow-up only (n=608) groups.

Setting.
—Eight sites serving diverse populations.

Participants.
—At age 8 years, 874 children were assessed: 336 in the intervention group and 538 in the follow-up only group.

Intervention.
—The 3-year intervention consisted of home visits (birth to 3 years), child development center services (ages 1 to 3 years), and parent group meetings (ages 1 to 3 years).

Primary Outcome Measures.
—Cognitive functioning (Weschler Intelligence Scale for Children-Ill; Peabody Picture Vocabulary Test-Revised); academic achievement (Woodcock-Johnson Tests of Achievement-Revised); and parental reports of school performance, behavior (Child Behavior Checklist), and health (Child General Health Survey).

Results.
—At age 8 years, in the entire cohort and in the lighter LBW stratum, the intervention and follow-up only groups were similar on all primary outcome measures. Differences favoring the intervention group were found within the heavier LBW group: full-scale IQ score (4.4 points higher, P=.007), verbal IQ score (4.2 points higher, P=.01 ), performance IQ score (3.9 points higher, P=.02), mathematics achievement score (4.8 points higher, P=.04), and receptive vocabulary score (6.7 points higher, P=.001 ). On a physical functioning subscale, the whole intervention group received less favorable ratings, while the lighter LBW intervention group had lower maternal ratings assessing social limitations caused by behavior.

Conclusion.
—Although at age 8 years there were modest intervention-related differences in the cognitive and academic skills of heavier LBW premature children, attenuation of the large favorable effects seen at 3 years was observed in both the heavier and lighter LBW groups. This indicates a need to develop additional intervention strategies for LBW premature children that can provide sustained benefits.



Author Affiliations

for the Infant Health and Development Program Research Group

From the Albert Einstein College of Medicine, Bronx, NY (Dr McCarton); Center for Children and Families, Teachers College, Columbia University, New York, NY (Dr Brooks-Gunn); Research Triangle Institute, Research Triangle Park, NC (Dr Wallace); Department of Pediatrics, University of Miami School of Medicine, Miami, Fia (Dr Bauer); Department of Pediatrics, University of Washington, Seattle (Drs Bennett and Scott); Children's Hospital of Philadelphia, University of Pennsylvania (Dr Bernbaum); Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock (Dr Casey); Department of Maternal and Child Health, Children's Hospital, Boston, Mass (Dr McCormick); Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas (Drs Tyson and Broyles); and Department of Biostatistics and Epidemiology, Johns Hopkins University, Baltimore, Md (Drs Tonascia and Meinen).


Footnotes

For a complete list of participants in the Infant Health and Development Program, see JAMA. 1990;263: 3035-3070, and JAMA. 1994;272:1257-1262.

Reprints: Cecelia McCarton, MD, Albert Einstein College of Medicine, Rose F. Kennedy Center, Room 820, 1410 Pelham Parkway South, Bronx, NY 10461.



Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati     What's this?

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Attention disturbances are associated with low birth weight in an urban community but not a suburban community
Marlow
Evid. Based Ment. Health 2009;12:62-62.
FULL TEXT  

Triple Risk: Do Difficult Temperament and Family Conflict Increase the Likelihood of Behavioral Maladjustment in Children Born Low Birth Weight and Preterm?
Whiteside-Mansell et al.
J Pediatr Psychol 2009;34:396-405.
ABSTRACT | FULL TEXT  

"You Get What You Get": Unexpected Findings About Low-Income Parents' Negative Experiences With Community Resources
Silverstein et al.
Pediatrics 2008;122:e1141-e1148.
ABSTRACT | FULL TEXT  

Role of the Medical Home in Family-Centered Early Intervention Services
Council on Children With Disabilities
Pediatrics 2007;120:1153-1158.
ABSTRACT | FULL TEXT  

Reducing Premature Infants' Length of Stay and Improving Parents' Mental Health Outcomes With the Creating Opportunities for Parent Empowerment (COPE) Neonatal Intensive Care Unit Program: A Randomized, Controlled Trial
Melnyk et al.
Pediatrics 2006;118:e1414-e1427.
ABSTRACT | FULL TEXT  

Behavioural and emotional problems in very preterm and very low birthweight infants at age 5 years
Reijneveld et al.
Arch. Dis. Child. Fetal Neonatal Ed. 2006;91:F423-F428.
ABSTRACT | FULL TEXT  

Child Outcome Measures in the Study of Child Care Quality
Zaslow et al.
Eval Rev 2006;30:577-610.
ABSTRACT  

Impact of Prenatal and/or Postnatal Growth Problems in Low Birth Weight Preterm Infants on School-Age Outcomes: An 8-Year Longitudinal Evaluation
Casey et al.
Pediatrics 2006;118:1078-1086.
ABSTRACT | FULL TEXT  

Quality-of-Care Indicators for the Neurodevelopmental Follow-up of Very Low Birth Weight Children: Results of an Expert Panel Process.
Wang et al.
Pediatrics 2006;117:2080-2092.
ABSTRACT | FULL TEXT  

Associations of Maternal Age- and Parity-Related Factors With Trends in Low-Birthweight Rates: United States, 1980 Through 2000
Yang et al.
Am. J. Public Health 2006;96:856-861.
ABSTRACT | FULL TEXT  

Early Intervention in Low Birth Weight Premature Infants: Results at 18 Years of Age for the Infant Health and Development Program
McCormick et al.
Pediatrics 2006;117:771-780.
ABSTRACT | FULL TEXT  





HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1997 American Medical Association. All Rights Reserved.