Murine Models of Hyperhomocysteinemia and Their Vascular Phenotypes
Dayal and Lentz
Arterioscler. Thromb. Vasc. Bio. 2008;28:1596-1605.
ABSTRACT
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Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia
Dayal et al.
Am. J. Physiol. Heart Circ. Physiol. 2008;295:H816-H825.
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Prevalence and effects of gene-gene and gene-nutrient interactions on serum folate and serum total homocysteine concentrations in the United States: findings from the third National Health and Nutrition Examination Survey DNA Bank
Yang et al.
Am. J. Clin. Nutr. 2008;88:232-246.
ABSTRACT
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Mesna for Treatment of Hyperhomocysteinemia in Hemodialysis Patients: A Placebo-Controlled, Double-Blind, Randomized Trial
Urquhart et al.
CJASN 2008;3:1041-1047.
ABSTRACT
| FULL TEXT
The Homocysteine Paradox
Rodionov and Lentz
Arterioscler. Thromb. Vasc. Bio. 2008;28:1031-1033.
FULL TEXT
Plasma Homocysteine, but Not Folate or Vitamin B-12, Predicts Mortality in Older People in the United Kingdom
Dangour et al.
J. Nutr. 2008;138:1121-1128.
ABSTRACT
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Effect of Folic Acid and B Vitamins on Risk of Cardiovascular Events and Total Mortality Among Women at High Risk for Cardiovascular Disease: A Randomized Trial
Albert et al.
JAMA 2008;299:2027-2036.
ABSTRACT
| FULL TEXT
Homocysteine-Lowering B Vitamin Therapy in Cardiovascular Prevention--Wrong Again?
Lonn
JAMA 2008;299:2086-2087.
FULL TEXT
Did national folic acid fortification reduce socioeconomic and racial disparities in folate status in the US?
Dowd and Aiello
Int J Epidemiol 2008;0:dyn066v1-dyn066.
ABSTRACT
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Trends in Circulating Concentrations of Total Homocysteine among US Adolescents and Adults: Findings from the 1991-1994 and 1999-2004 National Health and Nutrition Examination Surveys
Pfeiffer et al.
Clin. Chem. 2008;54:801-813.
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Mechanisms and potential therapeutic targets for folic acid in cardiovascular disease
Moens et al.
Am. J. Physiol. Heart Circ. Physiol. 2008;294:H1971-H1977.
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Homocysteine Inhibits Arterial Endothelial Cell Growth Through Transcriptional Downregulation of Fibroblast Growth Factor-2 Involving G Protein and DNA Methylation
Chang et al.
Circ. Res. 2008;102:933-941.
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Folate, Vitamin B6, Vitamin B12, and Methionine Intakes and Risk of Stroke Subtypes in Male Smokers
Larsson et al.
Am J Epidemiol 2008;167:954-961.
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How Does Folic Acid Cure Heart Attacks?
Tian and Ingwall
Circulation 2008;117:1772-1774.
FULL TEXT
Predictive value of folate, vitamin B12 and homocysteine levels in late-life depression
Kim et al.
Br. J. Psychiatry 2008;192:268-274.
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Folic Acid and Multivitamin Supplement Use and Risk of Placental Abruption: A Population-based Registry Study
Nilsen et al.
Am J Epidemiol 2008;167:867-874.
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Dietary and supplementary betaine: acute effects on plasma betaine and homocysteine concentrations under standard and postmethionine load conditions in healthy male subjects
Atkinson et al.
Am. J. Clin. Nutr. 2008;87:577-585.
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Lowering Plasma Homocysteine Concentrations of Older Men and Women with Folate, Vitamin B-12, and Vitamin B-6 Does Not Affect the Proportion of (n-3) Long Chain Polyunsaturated Fatty Acids in Plasma Phosphatidylcholine
Crowe et al.
J. Nutr. 2008;138:551-555.
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Homocysteine lowering with folic acid and B vitamins in people with chronic kidney disease--results of the renal Hope-2 study
Mann et al.
Nephrol Dial Transplant 2008;23:645-653.
ABSTRACT
| FULL TEXT
Homocysteine Induces Monocyte Chemoattractant Protein-1 Expression in Hepatocytes Mediated via Activator Protein-1 Activation
Woo et al.
J. Biol. Chem. 2008;283:1282-1292.
ABSTRACT
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Cardiovascular Risk Factors and Venous Thromboembolism: A Meta-Analysis
Ageno et al.
Circulation 2008;117:93-102.
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Hypermethylation of Fads2 and Altered Hepatic Fatty Acid and Phospholipid Metabolism in Mice with Hyperhomocysteinemia
Devlin et al.
J. Biol. Chem. 2007;282:37082-37090.
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S-Adenosylhomocysteine a better indicator of vascular disease than homocysteine?
Wagner and Koury
Am. J. Clin. Nutr. 2007;86:1581-1585.
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The risk of venous and arterial thrombosis in hyperhomocysteinemic subjects may be a result of elevated factor VIII levels
Lijfering et al.
haematol 2007;92:1703-1706.
ABSTRACT
| FULL TEXT
Coronary artery disease risk factors in patients with schizophrenia: effects of short term antipsychotic treatment
Sarandol et al.
J Psychopharmacol 2007;21:857-863.
ABSTRACT
B Vitamin Plasma Levels and the Risk of Ischemic Stroke and Transient Ischemic Attack in a German Cohort
Weikert et al.
Stroke 2007;38:2912-2918.
ABSTRACT
| FULL TEXT
The association between betaine and choline intakes and the plasma concentrations of homocysteine in women
Chiuve et al.
Am. J. Clin. Nutr. 2007;86:1073-1081.
ABSTRACT
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Association of blood lead and homocysteine levels among lead exposed subjects in Vietnam and Singapore
Chia et al.
Occup. Environ. Med. 2007;64:688-693.
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Atorvastatin therapy improves endothelial-dependent vasodilation in patients with systemic lupus erythematosus: an 8 weeks controlled trial
Ferreira et al.
Rheumatology (Oxford) 2007;46:1560-1565.
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Effect of Homocysteine Lowering on Mortality and Vascular Disease in Advanced Chronic Kidney Disease and End-stage Renal Disease: A Randomized Controlled Trial
Jamison et al.
JAMA 2007;298:1163-1170.
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B Vitamins for the Prevention of Vascular Disease: Insufficient Evidence to Justify Treatment
Baigent and Clarke
JAMA 2007;298:1212-1214.
FULL TEXT
Folic acid improves vascular reactivity in humans: a meta-analysis of randomized controlled trials
de Bree et al.
Am. J. Clin. Nutr. 2007;86:610-617.
ABSTRACT
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Endogenous Sex Hormones as Risk Factors for Dementia in Elderly Men and Women
Ravaglia et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2007;62:1035-1041.
ABSTRACT
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The heritability of plasma homocysteine, and the influence of genetic variation in the homocysteine methylation pathway
Siva et al.
QJM 2007;100:495-499.
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High frequency of vitamin B12 deficiency in asymptomatic individuals homozygous to MTHFR C677T mutation is associated with endothelial dysfunction and homocysteinemia
Zittan et al.
Am. J. Physiol. Heart Circ. Physiol. 2007;293:H860-H865.
ABSTRACT
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Homocysteine and Cardiovascular Risk: Considering the Evidence in the Context of Study Design, Folate Fortification, and Statistical Power
Ueland and Clarke
Clin. Chem. 2007;53:807-809.
FULL TEXT
Lowering Homocysteine with B Vitamins Has No Effect on Blood Pressure in Older Adults
McMahon et al.
J. Nutr. 2007;137:1183-1187.
ABSTRACT
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Homocysteine, 5,10-Methylenetetrahydrofolate Reductase 677C>T Polymorphism, Nutrient Intake, and Incident Cardiovascular Disease in 24 968 Initially Healthy Women
Zee et al.
Clin. Chem. 2007;53:845-851.
ABSTRACT
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Folic Acid Supplementation and Cardiovascular Diseases
Dentali et al.
JAMA 2007;297:1549-1550.
FULL TEXT
A comprehensive view of sex-specific issues related to cardiovascular disease
Pilote et al.
CMAJ 2007;176:S1-S44.
ABSTRACT
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Both vitamin B6 and total homocysteine plasma levels predict long-term atherothrombotic events in healthy subjects
Vanuzzo et al.
Eur Heart J 2007;28:484-491.
ABSTRACT
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Homocysteine, B vitamins, and the risk of dementia
Clarke
Am. J. Clin. Nutr. 2007;85:329-330.
FULL TEXT
Lowering homocysteine with B vitamins has no effect on biomarkers of bone turnover in older persons: a 2-y randomized controlled trial
Green et al.
Am. J. Clin. Nutr. 2007;85:460-464.
ABSTRACT
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Cardiovascular Fitness Is Negatively Associated With Homocysteine Levels in Female Adolescents
Ruiz et al.
Arch Pediatr Adolesc Med 2007;161:166-171.
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Levels of homocysteine are increased in metabolic syndrome patients but are not associated with an increased cardiovascular risk, in contrast to patients without the metabolic syndrome
Hajer et al.
Heart 2007;93:216-220.
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Elevated Homocysteine Is Associated With Reduced Regional Left Ventricular Function: The Multi-Ethnic Study of Atherosclerosis
Nasir et al.
Circulation 2007;115:180-187.
ABSTRACT
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The reverse epidemiology of plasma total homocysteine as a mortality risk factor is related to the impact of wasting and inflammation
Suliman et al.
Nephrol Dial Transplant 2007;22:209-217.
ABSTRACT
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Prothrombotic Effects of Hyperhomocysteinemia and Hypercholesterolemia in ApoE-Deficient Mice
Wilson et al.
Arterioscler. Thromb. Vasc. Bio. 2007;27:233-240.
ABSTRACT
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Using Genetic Variation to Optimize Nutritional Preemption
Gillies and Krul
J. Nutr. 2007;137:270S-274S.
ABSTRACT
| FULL TEXT
Effect of Folic Acid Supplementation on Risk of Cardiovascular Diseases: A Meta-analysis of Randomized Controlled Trials
Bazzano et al.
JAMA 2006;296:2720-2726.
ABSTRACT
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Methylmalonic acid and cognitive function in the Medical Research Council Cognitive Function and Ageing Study
McCracken et al.
Am. J. Clin. Nutr. 2006;84:1406-1411.
ABSTRACT
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Elevated serum S-adenosylhomocysteine in cobalamin-deficient elderly and response to treatment
Stabler et al.
Am. J. Clin. Nutr. 2006;84:1422-1429.
ABSTRACT
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Apolipoprotein E e4 allele affects risk of hyperhomocysteinemia in the elderly
Ravaglia et al.
Am. J. Clin. Nutr. 2006;84:1473-1480.
ABSTRACT
| FULL TEXT
Methods of detecting atherosclerosis in non-cardiac surgical patients; the role of biochemical markers
Howard-Alpe et al.
Br J Anaesth 2006;97:758-769.
ABSTRACT
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Regression dilution methods for meta-analysis: assessing long-term variability in plasma fibrinogen among 27 247 adults in 15 prospective studies
The Fibrinogen Studies Collaboration
Int J Epidemiol 2006;35:1570-1578.
ABSTRACT
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Bound Homocysteine, Cysteine, and Cysteinylglycine Distribution between Albumin and Globulins
Hortin et al.
Clin. Chem. 2006;52:2258-2264.
ABSTRACT
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Folic acid, homocysteine, and cardiovascular disease: judging causality in the face of inconclusive trial evidence
Wald et al.
BMJ 2006;333:1114-1117.
FULL TEXT
Endothelial Nitric Oxide Synthase Gene Polymorphisms and Cardiovascular Disease: A HuGE Review
Casas et al.
Am J Epidemiol 2006;164:921-935.
ABSTRACT
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A dual-isotope-labeling method of studying the bioavailability of hexaglutamyl folic acid relative to that of monoglutamyl folic acid in humans by using multiple orally administered low doses.
Melse-Boonstra et al.
Am. J. Clin. Nutr. 2006;84:1128-1133.
ABSTRACT
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Relationship of vascular risk to the progression of Alzheimer disease
Regan et al.
Neurology 2006;67:1357-1362.
ABSTRACT
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Asymmetrical dimethylarginine regulates endothelial function in methionine-induced but not in chronic homocystinemia in humans: effect of oxidative stress and proinflammatory cytokines.
Antoniades et al.
Am. J. Clin. Nutr. 2006;84:781-788.
ABSTRACT
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Vitamin-mineral supplementation and the progression of atherosclerosis: a meta-analysis of randomized controlled trials.
Bleys et al.
Am. J. Clin. Nutr. 2006;84:880-887.
ABSTRACT
| FULL TEXT
Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia
Dayal et al.
Blood 2006;108:2237-2243.
ABSTRACT
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Homocysteine and Cardiovascular Disease: Is HDL the Link?
Barter and Rye
Circ. Res. 2006;99:565-566.
FULL TEXT
Homocysteine Hypothesis for Atherothrombotic Cardiovascular Disease: Not Validated
Kaul et al.
J Am Coll Cardiol 2006;48:914-923.
ABSTRACT
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Obese Children and Adolescents: A Risk Group for Low Vitamin B12 Concentration.
Pinhas-Hamiel et al.
Arch Pediatr Adolesc Med 2006;160:933-936.
ABSTRACT
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Protective Mechanisms against Homocysteine Toxicity: THE ROLE OF BLEOMYCIN HYDROLASE
Zimny et al.
J. Biol. Chem. 2006;281:22485-22492.
ABSTRACT
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Trials that matter: should we routinely measure homocysteine levels and "treat" mild hyperhomocysteinemia?
Rosenberg and Mulrow
ANN INTERN MED 2006;145:226-227.
FULL TEXT
Fibrinogen and coronary heart disease: test of causality by 'Mendelian randomization'
Keavney et al.
Int J Epidemiol 2006;35:935-943.
ABSTRACT
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Homocysteine, B vitamins, and cardiovascular disease.
de Craen et al.
NEJM 2006;355:205-206.
FULL TEXT
Impaired Inhibitory Effect of Interleukin-10 on the Balance Between Matrix Metalloproteinase-9 and Its Inhibitor in Mononuclear Cells From Hyperhomocysteinemic Subjects
Holven et al.
Stroke 2006;37:1731-1736.
ABSTRACT
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Novel Genomic Loci Influencing Plasma Homocysteine Levels
Kullo et al.
Stroke 2006;37:1703-1709.
ABSTRACT
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Vitamins and entacapone in levodopa-induced hyperhomocysteinemia: A randomized controlled study
Postuma et al.
Neurology 2006;66:1941-1943.
ABSTRACT
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Primary Prevention of Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline.
Goldstein et al.
Circulation 2006;113:e873-e923.
ABSTRACT
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Dietary patterns are associated with biochemical markers of inflammation and endothelial activation in the Multi-Ethnic Study of Atherosclerosis (MESA)
Nettleton et al.
Am. J. Clin. Nutr. 2006;83:1369-1379.
ABSTRACT
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Vitamin and carotenoid status in older women: associations with the frailty syndrome.
Michelon et al.
J. Gerontol. A Biol. Sci. Med. Sci. 2006;61:600-607.
ABSTRACT
| FULL TEXT
The Many Facets of Hyperhomocysteinemia: Studies from the Framingham Cohorts
Selhub
J. Nutr. 2006;136:1726S-1730S.
ABSTRACT
| FULL TEXT
The Hordaland Homocysteine Study: A Community-Based Study of Homocysteine, Its Determinants, and Associations with Disease
Refsum et al.
J. Nutr. 2006;136:1731S-1740S.
ABSTRACT
| FULL TEXT
Primary Prevention of Ischemic Stroke: A Guideline From the American Heart Association/American Stroke Association Stroke Council: Cosponsored by the Atherosclerotic Peripheral Vascular Disease Interdisciplinary Working Group; Cardiovascular Nursing Council; Clinical Cardiology Council; Nutrition, Physical Activity, and Metabolism Council; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: The American Academy of Neurology affirms the value of this guideline.
Goldstein et al.
Stroke 2006;37:1583-1633.
ABSTRACT
| FULL TEXT
Biomarkers of Cardiovascular Disease: Molecular Basis and Practical Considerations
Vasan
Circulation 2006;113:2335-2362.
FULL TEXT
Confounding of the Relation between Homocysteine and Peripheral Arterial Disease by Lead, Cadmium, and Renal Function
Guallar et al.
Am J Epidemiol 2006;163:700-708.
ABSTRACT
| FULL TEXT
Homocysteine Trials -- Clear Outcomes for Complex Reasons
Loscalzo
NEJM 2006;354:1629-1632.
FULL TEXT
Homocysteine Lowering and Cardiovascular Events after Acute Myocardial Infarction
Bonaa et al.
NEJM 2006;354:1578-1588.
ABSTRACT
| FULL TEXT
Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
The Heart Outcomes Prevention Evaluation (HOPE) 2
NEJM 2006;354:1567-1577.
ABSTRACT
| FULL TEXT
Relationship Between Homocysteine and Mortality in Chronic Kidney Disease
Menon et al.
Circulation 2006;113:1572-1577.
ABSTRACT
| FULL TEXT
Improvement in Stroke Mortality in Canada and the United States, 1990 to 2002
Yang et al.
Circulation 2006;113:1335-1343.
ABSTRACT
| FULL TEXT
ApoA-I: A Missing Link Between Homocysteine and Lipid Metabolism?
Devlin and Lentz
Circ. Res. 2006;98:431-433.
FULL TEXT
Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population
Devlin et al.
Am. J. Clin. Nutr. 2006;83:708-713.
ABSTRACT
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Garlic Reduces Dementia and Heart-Disease Risk
Borek
J. Nutr. 2006;136:810S-812S.
ABSTRACT
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