Adiponectin Suppresses Pathological Microvessel Formation in Retina Through Modulation of Tumor Necrosis Factor-{alpha} Expression
Higuchi et al.
Circ. Res. 2009;104:1058-1065.
ABSTRACT
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Garlic Increases Antioxidant Levels in Diabetic and Hypertensive Rats Determined by a Modified Peroxidase Method
Drobiova et al.
Evid Based Complement Alternat Med 2009;0:nep011v1-nep011.
ABSTRACT
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The pathologic continuum of diabetic vascular disease.
Orasanu and Plutzky
J Am Coll Cardiol 2009;53:S35-S42.
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Prevention of Posterior Capsular Opacification through Aldose Reductase Inhibition
Yadav et al.
IOVS 2009;50:752-759.
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Endothelial Dysfunction in Mice with Streptozotocin-induced Type 1 Diabetes Is Opposed by Compensatory Overexpression of Cyclooxygenase-2 in the Vasculature
Nacci et al.
Endocrinology 2009;150:849-861.
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MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy
Wang et al.
FASEB J. 2008;22:4126-4135.
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Inhibition of Protein Kinase C{beta} Prevents Foam Cell Formation by Reducing Scavenger Receptor A Expression in Human Macrophages
Osto et al.
Circulation 2008;118:2174-2182.
ABSTRACT
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Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting
Cade
ptjournal 2008;88:1322-1335.
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Circulating Endothelial Progenitor Cells as a New Marker of Endothelial Dysfunction or Repair in Acute Stroke * Supplemental Methods
Chu et al.
Stroke 2008;39:1441-1447.
ABSTRACT
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Demonstration of the Essential Role of Protein Kinase C Isoforms in Hyperglycemia-Induced Embryonic Malformations
Zhiyong Zhao et al.
Reproductive Sciences 2008;15:349-356.
ABSTRACT
Inhibition of NADPH Oxidase Prevents Advanced Glycation End Product-Mediated Damage in Diabetic Nephropathy Through a Protein Kinase C-{alpha}-Dependent Pathway
Thallas-Bonke et al.
Diabetes 2008;57:460-469.
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Oral Hypoglycemics and Diabetic Nephropathy
Hadler
CJASN 2008;3:159-162.
FULL TEXT
Does Lowering of Blood Glucose Improve Cardiovascular Morbidity and Mortality?
Iqbal and Rubenstein
CJASN 2008;3:163-167.
FULL TEXT
Dynamic blood pressure load and nephropathy in the ZSF1 (fa/facp) model of type 2 diabetes
Griffin et al.
Am. J. Physiol. Renal Physiol. 2007;293:F1605-F1613.
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Akt activation and augmented fibronectin production in hyperhexosemia
Xin et al.
Am. J. Physiol. Endocrinol. Metab. 2007;293:E1036-E1044.
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Relationship Between Gilbert Syndrome and Prevalence of Vascular Complications in Patients With Diabetes
Inoguchi et al.
JAMA 2007;298:1398-1400.
FULL TEXT
Painful Diabetic Peripheral Neuropathy
Smith
J. Am. Podiatr. Med. Assoc. 2007;97:394-401.
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Aldose Reductase-Regulated Tumor Necrosis Factor-{alpha} Production Is Essential for High Glucose-Induced Vascular Smooth Muscle Cell Growth
Ramana et al.
Endocrinology 2007;148:4371-4384.
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Etiology and natural history of diabetic retinopathy: An overview
Morello
Am J Health Syst Pharm 2007;64:S3-S7.
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Screening for and managing diabetic retinopathy: Current approaches
Bloomgarden
Am J Health Syst Pharm 2007;64:S8-S14.
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New pharmacologic approachesto treating diabetic retinopathy
Ryan
Am J Health Syst Pharm 2007;64:S15-S21.
ABSTRACT
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Phosphorylation of Pleckstrin Increases Proinflammatory Cytokine Secretion by Mononuclear Phagocytes in Diabetes Mellitus
Ding et al.
J. Immunol. 2007;179:647-654.
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Kidney Outcomes in Long-Term Studies of Ruboxistaurin for Diabetic Eye Disease
Tuttle et al.
CJASN 2007;2:631-636.
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High Glucose Impairs Early and Late Endothelial Progenitor Cells by Modifying Nitric Oxide-Related but Not Oxidative Stress-Mediated Mechanisms
Chen et al.
Diabetes 2007;56:1559-1568.
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CAN WE OVERCOME THE PREDESTINED POOR SURVIVAL OF DIABETIC PATIENTS? PERSPECTIVES FROM PRE- AND POST-DIALYSIS
Kim
pdi 2007;27:S171-S175.
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Etiology and effect on outcomes of hyperglycemia in hospitalized patients
Campbell
Am J Health Syst Pharm 2007;64:S4-S8.
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A 6-Month, Randomized, Double-Masked, Placebo-Controlled Study Evaluating the Effects of the Protein Kinase C-{beta} Inhibitor Ruboxistaurin on Skin Microvascular Blood Flow and Other Measures of Diabetic Peripheral Neuropathy
Casellini et al.
Diabetes Care 2007;30:896-902.
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Effect of Ruboxistaurin on Urinary Transforming Growth Factor-{beta} in Patients With Diabetic Nephropathy and Type 2 Diabetes
Gilbert et al.
Diabetes Care 2007;30:995-996.
FULL TEXT
Effect of Ruboxistaurin in Patients With Diabetic Macular Edema: Thirty-Month Results of the Randomized PKC-DMES Clinical Trial
The PKC-DMES Study Group
Arch Ophthalmol 2007;125:318-324.
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Glycosylation Mediates Up-regulation of a Potent Antiangiogenic and Proatherogenic Protein, Thrombospondin-1, by Glucose in Vascular Smooth Muscle Cells
Raman et al.
J. Biol. Chem. 2007;282:5704-5714.
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Spontaneously reduced blood pressure load in the rat streptozotocin-induced diabetes model: potential pathogenetic relevance
Bidani et al.
Am. J. Physiol. Renal Physiol. 2007;292:F647-F654.
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Role of Nitric Oxide in High Glucose-Induced Mitogenic Response in Renal Fibroblasts
Chuang et al.
Mol. Endocrinol. 2006;20:2548-2558.
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New-onset diabetes and risk of all-cause and cardiovascular mortality: the cardiovascular health study.
Smith et al.
Diabetes Care 2006;29:2012-2017.
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Folate and Vitamin B6 Rapidly Normalize Endothelial Dysfunction In Children With Type 1 Diabetes Mellitus
MacKenzie et al.
Pediatrics 2006;118:242-253.
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Reexamining the hyperglycemic pseudohypoxia hypothesis of diabetic oculopathy.
Diederen et al.
IOVS 2006;47:2726-2731.
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Endothelins: regulators of extracellular matrix protein production in diabetes.
Khan et al.
Exp. Biol. Med. 2006;231:1022-1029.
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Temporal expression profile and distribution pattern indicate a role of connective tissue growth factor (CTGF/CCN-2) in diabetic nephropathy in mice
Roestenberg et al.
Am. J. Physiol. Renal Physiol. 2006;290:F1344-F1354.
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Contribution of aldose reductase to diabetic hyperproliferation of vascular smooth muscle cells.
Srivastava et al.
Diabetes 2006;55:901-910.
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Angiotensin II Type 1 Receptor Blockers Reduce Urinary Oxidative Stress Markers in Hypertensive Diabetic Nephropathy
Ogawa et al.
Hypertension 2006;47:699-705.
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Effects of a Single Administration of Acarbose on Postprandial Glucose Excursion and Endothelial Dysfunction in Type 2 Diabetic Patients: A Randomized Crossover Study
Shimabukuro et al.
J. Clin. Endocrinol. Metab. 2006;91:837-842.
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Orally Active Neurotrophin-Enhancing Agent Protects Against Dysfunctions of the Peripheral Nerves in Hyperglycemic Animals
Kakinoki et al.
Diabetes 2006;55:616-621.
ABSTRACT
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De novo emergence of insulin-stimulated glucose uptake in human aortic endothelial cells incubated with high glucose
Gosmanov et al.
Am. J. Physiol. Endocrinol. Metab. 2006;290:E516-E522.
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Diabetic Microangiopathy in Ischemic Limb Is a Disease of Disturbance of the Platelet-Derived Growth Factor-BB/Protein Kinase C Axis but Not of Impaired Expression of Angiogenic Factors
Tanii et al.
Circ. Res. 2006;98:55-62.
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Posttranslational, Reversible O-Glycosylation Is Stimulated by High Glucose and Mediates Plasminogen Activator Inhibitor-1 Gene Expression and Sp1 Transcriptional Activity in Glomerular Mesangial Cells
Goldberg et al.
Endocrinology 2006;147:222-231.
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Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3
An et al.
Proc. Natl. Acad. Sci. USA 2005;102:16275-16280.
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Can Protein Kinase C {beta}-Selective Inhibitor, Ruboxistaurin, Stop Vascular Complications in Diabetic Patients?
He and King
Diabetes Care 2005;28:2803-2805.
FULL TEXT
Glycation and Carboxymethyllysine Levels in Skin Collagen Predict the Risk of Future 10-Year Progression of Diabetic Retinopathy and Nephropathy in the Diabetes Control and Complications Trial and Epidemiology of Diabetes Interventions and Complications Participants With Type 1 Diabetes
Genuth et al.
Diabetes 2005;54:3103-3111.
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Diabetes causes inhibition of glucose-6-phosphate dehydrogenase via activation of PKA, which contributes to oxidative stress in rat kidney cortex
Xu et al.
Am. J. Physiol. Renal Physiol. 2005;289:F1040-F1047.
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Activation of the Sphingosine Kinase-Signaling Pathway by High Glucose Mediates the Proinflammatory Phenotype of Endothelial Cells
Wang et al.
Circ. Res. 2005;97:891-899.
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Enhanced superoxide release and elevated protein kinase C activity in neutrophils from diabetic patients: association with periodontitis
Karima et al.
J. Leukoc. Biol. 2005;78:862-870.
ABSTRACT
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Ruboxistaurin, a Protein Kinase C {beta} Inhibitor, as an Emerging Treatment for Diabetes Microvascular Complications
Joy et al.
The Annals of Pharmacotherapy 2005;39:1693-1699.
ABSTRACT
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Angiogenic Pathways in Diabetic Retinopathy
Aiello
NEJM 2005;353:839-841.
FULL TEXT
Effect of Hepatic Lipase -514C->T Polymorphism and Its Interactions With Apolipoprotein C3 -482C->T and Apolipoprotein E Exon 4 Polymorphisms on the Risk of Nephropathy in Chinese Type 2 Diabetic Patients
Baum et al.
Diabetes Care 2005;28:1704-1709.
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The Effect of Ruboxistaurin on Visual Loss in Patients With Moderately Severe to Very Severe Nonproliferative Diabetic Retinopathy: Initial Results of the Protein Kinase C {beta} Inhibitor Diabetic Retinopathy Study (PKC-DRS) Multicenter Randomized Clinical Trial
The PKC-DRS Study Group
Diabetes 2005;54:2188-2197.
ABSTRACT
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Activation of p38 Has Opposing Effects on the Proliferation and Migration of Endothelial Cells
McMullen et al.
J. Biol. Chem. 2005;280:20995-21003.
ABSTRACT
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Elevated release of sCD40L from platelets of diabetic patients by thrombin, glucose and advanced glycation end products
Varo et al.
Diabetes and Vascular Disease Research 2005;2:81-87.
ABSTRACT
Role of Aldose Reductase and Oxidative Damage in Diabetes and the Consequent Potential for Therapeutic Options
Srivastava et al.
Endocr. Rev. 2005;26:380-392.
ABSTRACT
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Isolation of transcriptomal changes attributable to LHON mutations and the cybridization process
Danielson et al.
Brain 2005;128:1026-1037.
ABSTRACT
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Placental Dysfunction in Suramin-Treated Rats: Impact of Maternal Diabetes and Effects of Antioxidative Treatment
Nash et al.
Reproductive Sciences 2005;12:174-184.
ABSTRACT
Identification of Amadori-Modified Plasma Proteins in Type 2 Diabetes and the Effect of Short-Term Intensive Insulin Treatment
Jaleel et al.
Diabetes Care 2005;28:645-652.
ABSTRACT
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Requirement of Aldose Reductase for the Hyperglycemic Activation of Protein Kinase C and Formation of Diacylglycerol in Vascular Smooth Muscle Cells
Ramana et al.
Diabetes 2005;54:818-829.
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Hyperglycemia Induces Monocytic Release of Interleukin-6 via Induction of Protein Kinase C-{alpha} and -{beta}
Devaraj et al.
Diabetes 2005;54:85-91.
ABSTRACT
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Activation of Nulcear Factor-{kappa}B by Hyperglycemia in Vascular Smooth Muscle Cells Is Regulated by Aldose Reductase
Ramana et al.
Diabetes 2004;53:2910-2920.
ABSTRACT
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Meta-Analysis: Glycosylated Hemoglobin and Cardiovascular Disease in Diabetes Mellitus
Selvin et al.
ANN INTERN MED 2004;141:421-431.
ABSTRACT
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Accelerated Nephropathy in Diabetic Apolipoprotein E-Knockout Mouse: Role of Advanced Glycation End Products
Lassila et al.
J. Am. Soc. Nephrol. 2004;15:2125-2138.
ABSTRACT
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Diabetes Mellitus Non-Glucose Monitoring: Point-of-Care Testing
Armor and Britton
The Annals of Pharmacotherapy 2004;38:1039-1047.
ABSTRACT
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Connective Tissue Growth Factor Is Increased in Plasma of Type 1 Diabetic Patients With Nephropathy
Roestenberg et al.
Diabetes Care 2004;27:1164-1170.
ABSTRACT
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Multifocal Electroretinogram Delays Predict Sites of Subsequent Diabetic Retinopathy
Han et al.
IOVS 2004;45:948-954.
ABSTRACT
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Management of Diabetes and Hyperglycemia in Hospitals
Clement et al.
Diabetes Care 2004;27:553-591.
FULL TEXT
Amadori-configurated albumin induces nitric oxide-dependent apoptosis of endothelial cells: a possible mechanism of diabetic vasculopathy
Amore et al.
Nephrol Dial Transplant 2004;19:53-60.
ABSTRACT
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Endothelial Progenitor Cell Dysfunction: A Novel Concept in the Pathogenesis of Vascular Complications of Type 1 Diabetes
Loomans et al.
Diabetes 2004;53:195-199.
ABSTRACT
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Biochemical Pathways for Microvascular Complications of Diabetes Mellitus
Setter et al.
The Annals of Pharmacotherapy 2003;37:1858-1866.
ABSTRACT
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High Glucose-suppressed Endothelin-1 Ca2+ Signaling via NADPH Oxidase and Diacylglycerol-sensitive Protein Kinase C Isozymes in Mesangial Cells
Hua et al.
J. Biol. Chem. 2003;278:33951-33962.
ABSTRACT
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Protein Kinase C-Dependent Increase in Reactive Oxygen Species (ROS) Production in Vascular Tissues of Diabetes: Role of Vascular NAD(P)H Oxidase
Inoguchi et al.
J. Am. Soc. Nephrol. 2003;14:S227-232.
ABSTRACT
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Extracellular Matrix Metabolism in Diabetic Nephropathy
Mason and Wahab
J. Am. Soc. Nephrol. 2003;14:1358-1373.
ABSTRACT
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Glucose, Glycation, and RAGE: Implications for Amplification of Cellular Dysfunction in Diabetic Nephropathy
Wendt et al.
J. Am. Soc. Nephrol. 2003;14:1383-1395.
ABSTRACT
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Animal Models of Human Diabetic Polyneuropathy
Crawford and Hardwicke
JAMA 2003;289:1779-1780.
FULL TEXT
