 |
|
CLINICIAN'S CORNER
Assessing Benefits and Harms of Hormone Replacement Therapy
Clinical Applications
Heidi D. Nelson, MD,MPH
JAMA. 2002;288:882-884.
An estimated one third of postmenopausal women in the United States use hormone replacement therapy (HRT) to treat symptoms of menopause and prevent chronic conditions. In the context of this widespread use, evidence has been growing about the potential harms of HRT, particularly regarding long-term use. Physicians and patients are often confused about how to use results of studies in individual cases. This article applies the current state of evidence for the benefits and harms of HRT to management decisions in 4 clinical situations. Patient preferences, as well as evidence, are important for these decisions. Benefits and harms need to be readdressed periodically to apply newly published evidence and to reassess emerging risks, comorbidities, and needs of individuals.
Author Affiliations: Division of Medical Informatics and Outcomes Research and Evidence-based Practice Center, and Department of Medicine, Oregon Health and Science University, and Medical Service, Veterans Affairs Medical Center, Portland, Ore.
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED ARTICLES
Postmenopausal Hormone Replacement Therapy: Scientific Review
, , , , and
JAMA. ;288():872-881.
FULL TEXT
Hormone Replacement Therapy
JAMA. ;288():916-916.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
National Use of Postmenopausal Hormone Therapy: Annual Trends and Response to Recent Evidence
Hersh et al.
JAMA 2004;291:47-53.
ABSTRACT
| FULL TEXT
Issues to debate on the Women's Health Initiative (WHI) study. Prescription attitudes among Belgian gynaecologists after premature discontinuation of the WHI study
Ena and Rozenberg
Hum Reprod 2003;18:2245-2248.
ABSTRACT
| FULL TEXT
|
