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Rebecca Voelker
JAMA contributor

JAMA. 1998;279:902.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Identification of a protein critical in iron metabolism could help boost understanding of iron-deficiency anemia and treatment for hemochromatosis.

In the February 3 issue of the Proceedings of the National Academy of Sciences, researchers at the State University of New York at Buffalo School of Medicine and Biomedical Sciences and Children's Hospital in Boston, Mass, describe their discovery of the protein, called Nramp2. "This finding allows us to take a major step forward in our understanding of iron metabolism," said Michael Garrick, PhD, professor of pediatrics and biochemistry at the State University of New York and coauthor of the study.

The new finding comes from 3 decades of research on iron-deficiency anemia in animal models. The researchers said their study demonstrates that Nramp2 is implicated in at least 2, and possibly 3, important functions in iron metabolism: taking up iron in the gastrointestinal tract, delivering iron to . . . [Full Text of this Article]

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