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A Cure for the Common Cold?
Zinc Again
Anne Gadomski, MD, MPH
JAMA. 1998;279:1999-2000.
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The study reported by Macknin et al1 in this issue of THE JOURNAL on zinc gluconate lozenges for treating children with the common cold represents yet another wave of single-agent assaults on this common malady. The evidence this study provides is welcome, even though no beneficial effects of zinc lozenges on treatment of the common cold among school-aged children are demonstrated. The authors are laudably forthcoming regarding the potential biases in their well-executed study. They also set an appropriately high methodologic standard for future studies and allude to design improvements in future trials that will advance this field.
It is notable that children in the study still experienced adverse effects at what the authors consider to be relatively low doses of zinc lozenges (a total of 50-60 mg/d). These adverse effects probably enabled the students to discern what treatment they were receiving. Zinc lozenge–related adverse effects, . . . [Full Text of this Article]
From the Research Institute at Bassett Hospital, Cooperstown, NY.
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