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Charles Marwick

JAMA. 1998;279:344-345.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A STRENGTHENED system for ensuring that human research subjects are adequately protected is beginning to emerge. Two proposals aimed at improving the current system were outlined at a meeting of the National Bioethics Advisory Commission last month in Washington, DC. One of the charges to the commission, created by President Clinton in 1995, was to review the way the rights and welfare of human research subjects are protected. Some commission members are convinced there is need for change.

Critics say the problem is an inherent conflict of interest in the current system. The Office for Protection from Research Risks (OPRR), the body that oversees the ethical conduct of research, is placed within the National Institutes of Health (NIH), which conducts or funds the research the office is supposed to police. The OPRR is also overburdened. The commissioners were reminded that it has responsibility for 450 multicenter projects, 3000 . . . [Full Text of this Article]

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