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Studies Reveal Early Impact of HIV Infection, Effects of Treatment
Joan Stephenson, PhD
JAMA. 1998;279:641-642.
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NEW STUDIES about events early in the course of infection with the human immunodeficiency virus (HIV) may have important implications in treating the infection, namely, when clinicians should institute aggressive anti-HIV therapy. Results of these studies and other findings, including information about the emergence of unusual adverse effects in patients treated with protease inhibitors and the earliest evidence about when HIV infection appeared in the human population, were among the discoveries reported at the Fifth Conference on Retroviruses and Opportunistic Infections held in Chicago, Ill, last month.
How Crucial is Early Treatment?
Initiating treatment with a potent combination of antiretroviral drugs as soon as possible after infection with HIV may be critical to preserving a key element of the immune system, said Bruce D. Walker, MD, of Massachusetts General Hospital, Charlestown. New studies described by Walker suggest that for most HIV-infected people, virus-specific helper T cells are . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
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Oral Treatment with Trimethoprim-Sulfamethoxazole and Zidovudine Suppresses Murine Accessory Cell-Dependent Immune Responses
Freund et al.
Toxicol Sci 2000;55:335-342.
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