This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Contact me when this article is cited  Related Content  • Similar articles in JAMA  Social Bookmarking   What's this?

vols 1 & 2, edited by Mark Feldman, Bruce F. Scharschmidt, and Marvin H. Sleisenger, 6th ed, 2046 pp, with illus, $195, ISBN 0-7216-6291-9, Philadelphia, Pa, WB Saunders Co, 1997.

JAMA. 1998;279:715-716.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The first edition of this text in 1973 totally altered gastrointestinal teaching and patient care, for it was heavily based on the most current pathophysiological science, then physiology. Prominent clinician investigators contributed most of the chapters, and the editorial approach emphasized basic science–based diagnosis and treatment. No text in English was comparable.

In the ensuing years, the cutting edge of basic science has shifted from physiology to biochemistry to molecular biology and genetics. Clinical science has given increasing credence to blind, randomized, controlled trials and meta-analysis and less to actual experience. With these changes in gastroenterology and the appearance of outstanding competing texts, there have been large changes in Sleisenger and Fordtran. The greatest change came in the fifth edition of 1993, when two new editors, Bruce Scharschmidt and Mark Feldman, were added, and, as a result, the pathophysiology portions were refocused on the current science of molecular biology. . . . [Full Text of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?