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William J. Burman, MD; Randall R. Reves, MD; David L. Cohn, MD

JAMA. 1998;280:93-95.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

THE LAST 3 years have been a remarkable time to be involved in the care of patients with human immunodeficiency virus (HIV) infection. Improvements in antiretroviral therapy have decreased the rates of death and opportunistic infections by about 70% in our clinic (W.J.B., R.R.R., and D.L.C., unpublished data, 1998) and brought an atmosphere of hope to patients and clinicians. However, we read with concern the 1997 recommendations from the International AIDS Society–USA Panel regarding the use of therapy for all patients with an HIV RNA level greater than 5000 to 10000 copies/mL, regardless of CD4 cell count.¹ Aggressive treatment of early HIV infection was also recommended by a panel convened by the Department of Health and Human Services.² The Department of Health and Human Services panel was more conservative and presented the potential advantages and disadvantages of aggressive, . . . [Full Text of this Article]

From the Infectious Diseases/AIDS Clinic, Denver Public Health and the Department of Medicine, Division of Infectious Disease, University of Colorado Health Sciences Center, Denver.

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