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Haemophilus influenzae Invasive Disease Among Children Aged <5 YearsCalifornia, 1990-1996
JAMA. 1998;280:1130-1131.
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MMWR. 1998;47:737-740
3 tables omitted
HAEMOPHILUS influenzae (Hi) causes a variety of severe clinical illnesses including meningitis, pneumonia, epiglottitis, and septic arthritis.1 In the prevaccine era (i.e., before 1988),Haemophilus influenzae type b (Hib) caused approximately 95% of the Hi invasive disease among children aged <5 years.1 In 1988, Hib conjugate vaccines were introduced for use among children aged 18 months-5 years; they were subsequently recommended for routine use in infants by the Advisory Committee on Immunization Practices (ACIP) in 1990.2 During 1989-1995, Hib invasive disease among children aged <5 years declined 95% nationally.3 To document the decline of Hib invasive disease and to examine the epidemiology of reported nontype b Hi invasive disease among children aged <5 years, CDC, in collaboration with the California Department of Health Services, analyzed reported cases in California from 1990 to 1996. This report summarizes the results of the analysis and documents the decline . . . [Full Text of this Article]
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