 |
|
Saving the Vision of Children With Juvenile Rheumatoid Arthritis–Associated Uveitis
Quan Dong Nguyen, MS, MD;
C. Stephen Foster, MD
JAMA. 1998;280:1133-1134.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
INTRODUCTION
CHRONIC UVEITIS is a serious complication of juvenile rheumatoid arthritis (JRA). Approximately 6% of all cases of uveitis occur in children,1 and up to 80% of all cases of anterior uveitis in childhood are associated with JRA.2 Although remarkable progress has been made in the care of patients with JRA-associated uveitis since the development of corticosteroids for systemic and ophthalmic use in the 1950s, up to 12% of children with uveitis associated with pauciarticular JRA still develop permanent blindness as a result of low-grade chronic intraocular inflammation.3 Ironically, these children are often under careful observation by ophthalmologists who may opt to tolerate low-grade ocular inflammation, hoping to avoid the development of corticosteroid-induced ocular adverse effects such as cataracts and glaucoma.4 The vision-robbing consequences of low-grade uveitis occur extremely slowly, typically over a period of 4 to 8 years, and the end . . . [Full Text of this Article]
Epidemiology
Diagnosis and Course
Therapy
From the Ocular Immunology and Uveitis Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston.
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Etanercept and uveitis in patients with juvenile idiopathic arthritis
Schmeling and Horneff
Rheumatology (Oxford) 2005;44:1008-1011.
ABSTRACT
| FULL TEXT
Uveitis and juvenile arthritis
Rosenbaum and Smith
Br. J. Ophthalmol. 2002;86:1-2.
FULL TEXT
|
