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John P. Burke, MD

JAMA. 1998;280:1270-1271.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The need for responsible antibiotic use stewardship to quell microbial resistance should have no disputants. Indeed, there have been so many clarion calls for action¹ to halt the increasing resistance to antimicrobials that further emphasis seems redundant. The list of august organizations and agencies that have highlighted the problems of antibiotic resistance in recent years includes the National Academy of Sciences, Institute of Medicine, the Infectious Diseases Society of America, the Centers for Disease Control and Prevention; the American Society for Microbiology, and the World Health Organization. The National Foundation for Infectious Diseases has ranked antimicrobial resistance and emerging infections as the first among the top 10 problems in infectious diseases on which it will concentrate its efforts.²

The unprecedented level of concern about increasing drug resistance, both in the community and in hospitals and involving a wide variety of human pathogens, reflects the growing frustration . . . [Full Text of this Article]

From the Department of Clinical Epidemiology and Infectious Disease, LDS Hospital, Salt Lake City, Utah.

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