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Simian Virus 40Contaminated Polio Vaccine and Cancer Rates
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To the Editor. In their report on contamination of poliovirus vaccine with simian virus 40 (SV40), Dr Strickler and colleagues1 mistakenly claim that "earlier studies of cancer risk following exposure to SV40-contaminated vaccine were generally limited by small sample size or short follow-up." I refute this suggestion and contend that my report,2 which they include in this group, neither was of limited sample size nor was it a short follow-up as arguably the others they refer to were.
The sample totaled 810 children with malignant disease observed during 10 years in 2 major Australian hospitals and was not construed as limited in size or follow-up by either the reviewers or Editor of Nature . To include this report with the others Strickler et al consider limited and small is merely their perception, which conflicts with reality. The survey showed a significant association between the immunization with Salk vaccine and childhood . . . [Full Text of this Article]
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