 |
|
St John's Wort During Pregnancy
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
To the Editor.— With St John's wort (Hypericum perforatum) gaining popularity as a nonprescription, herbal treatment for depression we are concerned that women may assume that it is safe to take during pregnancy.
Review of MEDLINE and Reproductive Toxicity Review using the search terms St John's wort, Hypericum perforatum, hypericin, and Johanneskraut (German) revealed scant information. Increased uterine tonicity has been reported in animals,1 suggesting that use of this agent should be avoided during pregnancy.2 However, a study of toxic effects in rats and dogs at oral doses of 900 and 2700 mg/kg showed no reproductive effects.3 Also, a study of the mutagenic potential of hypericum extract on mammalian cells showed no effects.4 To date, there are no published cases, to our knowledge, of human antenatal exposure or lactation effects.
Patient 1
A 38-year-old woman experienced a recurrence of major depressive disorder during her first trimester of pregnancy. At . . . [Full Text of this Article]
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Complementary, Holistic, and Integrative Medicine: St. John's Wort
Charrois et al.
Pediatr. Rev. 2007;28:69-72.
FULL TEXT
Herbal medicine use is frequent in ambulatory surgery patients in Vancouver Canada: [L'usage de plante medicinale est frequent chez les patients de chirurgie ambulatoire a Vancouver, Canada]
Lennox and Henderson
Canadian J. Anesthesia 2003;50:21-25.
ABSTRACT
| FULL TEXT
Herbal Medicines and Perioperative Care
Ang-Lee et al.
JAMA 2001;286:208-216.
ABSTRACT
| FULL TEXT
Dietary Supplements and Natural Products as Psychotherapeutic Agents
Fugh-Berman and Cott
Psychosom. Med. 1999;61:712-728.
ABSTRACT
| FULL TEXT
|
