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To the Editor.—The University of North Carolina's CAGE (Cut down, Annoyed, Guilty, Eye opener) questionnaire is now so familiar that it is sometimes used without its source¹ being cited. Such is the case in a recent article in JAMA.²

The CAGE questionnaire was first described at an international conference and published in the proceedings of that meeting.³ There, and in my article in JAMA, I emphasized that a medical diagnosis of alcoholism should not be based solely on a questionnaire. Dr Bradley and colleagues² conclude that, for women, the reasonable cut point is answering positively to 1 or more of the CAGE questions. I agree, but I also apply this to men. As I stated, "The physician should use the questions to determine his index of suspicion that alcoholism may exist. Thus, even one positive reply calls for further inquiry."¹ Bradley et al² refer to "the . . . [Full Text of this Article]

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