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Thomas L. Delbanco, MD; Jennifer Daley, MD; Erin E. Hartman, MS
From the Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Ave, LY318, Boston, MA 02215.

JAMA. 1998;280:372.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In June 1997, at the Medicine Grand Rounds, Dr Anthony Komaroff discussed Ms H, an educator unable to work because of debilitating symptoms associated with a 2-year history of chronic fatigue. Her ailment, which began shortly after a flu-like illness, was marked primarily by weakness, fatigue, chronic insomnia, and depression that she felt was in response to her symptoms. In recent years she had felt somewhat less depressed, and wondered also if the disease might be slowly diminishing in its severity.

Dr Komaroff discussed the definition, prevalence, and epidemiology of chronic fatigue syndrome, including the differential diagnosis and the social stigmata associated with this diagnosis. He reviewed several lines of evidence focusing on the pathogenesis of chronic fatigue syndrome, and outlined current diagnostic and therapeutic strategies. We asked the patient and her primary physician to report on the year . . . [Full Text of this Article]

MS H, THE PATIENT



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