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To the Editor.—In 1988, the European Atherosclerosis Society recommended a therapeutic goal for cholesterol of 5.2 mmol/L (200 mg/dL) and for low-density lipoprotein cholesterol of 3.5 mmol/L (135 mg/dL) in patients with coronary heart disease.¹ These therapeutic goals preferably should be reached by dietary measures, but if hypercholesterolemia persists, drug therapy should be initiated. We wondered whether these recommendations, widely distributed in European countries, are accepted in clinical practice and have been influenced by the publication of the results of several secondary intervention studies with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors from 1990 to 1994 and new, more rigorous guidelines.^2-3

In 1988, the Bavarian Cholesterol Screening Project was initiated to achieve the early detection of subjects with an increased risk for cardiovascular disease based on hypercholesterolemia and to refer these subjects to further diagnostic tests and treatment if necessary. A total of 202987 subjects were screened in 321 campaigns (April . . . [Full Text of this Article]

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Toward Better Therapy of Hypercholesterolemia
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Arch Intern Med 2000;160:2685-2686.
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