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Rebecca Voelker
JAMA contributor

JAMA. 1998;280:687.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The question of homocysteine's link with heart disease has reared its head once again.

Recently, several studies have indicated that blood levels of homocysteine could be an independent predictor of heart disease. However, in the July 21 issue of Circulation: Journal of the American Heart Association, researchers at the University of Minnesota Medical School in Minneapolis reported that they did not find a causal relationship between homocysteine levels and heart disease.

The Minnesota researchers evaluated blood samples from 759 people aged 45 to 64 years during a 3-year period from 1987 to 1989, again between 1990 and 1992, and a third time between 1993 and 1995. During the study, 232 of the participants developed heart disease. But their findings demonstrated a stronger association between blood levels of vitamin B₆, which has been shown to reduce homocysteine levels and risk for heart disease.

In fact, the study . . . [Full Text of this Article]

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