This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (25)  • Contact me when this article is cited  Related Content  • Related letter  • Similar articles in JAMA  Social Bookmarking   What's this?

Joan Stephenson, PhD

JAMA. 1999;281:1069.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

CHICAGO—Clinicians giving potent combinations of antiretroviral drugs to patients with HIV to suppress the virus are finding just how much the effectiveness of such regimens depends on strict adherence.

Although there are many potential reasons—such as individual differences in drug absorption or metabolism—for the failure of highly active antiretroviral therapy (HAART) to keep a patient's HIV in check, experts believe the chief reason is poor adherence to treatment regimens, which can promote the emergence of drug-resistant strains. New findings presented at the 6th Conference on Retroviruses and Opportunistic Infections last month in Chicago underscored the importance of strict adherence in maintaining "virologic success"—sustained suppression of HIV—and examined factors associated with poor adherence.

PILL-TAKING MONITORED

To get a snapshot of how well 84 HIV-infected patients at two sites were adhering to treatment with protease inhibitors, researchers from the VA Medical Center in Pittsburgh and the University of . . . [Full Text of this Article]

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?

RELATED LETTER

Directly Observed Therapy to Treat HIV Infection in Prisoners
Sergio Babudieri, Antonio Aceti, Gian Piero D'Offizi, Sergio Carbonara, and Giulio Starnini
JAMA. 2000;284(2):179-180.
EXTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Adherence to Medical Regimens: Understanding the Effects of Cognitive Appraisal, Quality of Life, and Perceived Family Resiliency
Frain et al.
Rehabil Couns Bull 2009;52:237-250.
ABSTRACT  

Directly Observed Therapy to Treat HIV Infection in Prisoners
Babudieri et al.
JAMA 2000;284:179-180.
FULL TEXT  

Oral Treatment with Trimethoprim-Sulfamethoxazole and Zidovudine Suppresses Murine Accessory Cell-Dependent Immune Responses
Freund et al.
Toxicol Sci 2000;55:335-342.
ABSTRACT | FULL TEXT  

Short-cycle structured intermittent treatment of chronic HIV infection with highly active antiretroviral therapy: Effects on virologic, immunologic, and toxicity parameters
Dybul et al.
Proc. Natl. Acad. Sci. USA 2001;98:15161-15166.
ABSTRACT | FULL TEXT