You are seeing this message because your Web browser does not support basic Web standards. Find out more about why this message is appearing and what you can do to make your experience on this site better.


ABOUT JAMA
Advanced Search

Welcome   | My Account | E-mail Alerts | Access Rights | Sign In


  Vol. 281 No. 18, May 12, 1999 TABLE OF CONTENTS
  JAMA
  •  Online Features
  Letters
 This Article
 •Full text
 •PDF
 •Send to a friend
 • Save in My Folder
 •Save to citation manager
 •Permissions
 Citing Articles
 •Contact me when this article is cited
 Related Content
 •Similar articles in JAMA

Evidence Supporting Antileukotriene Agents for Asthma

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: In her article, Dr Wenzel1 states that evidence suggests that antileukotriene agents in combination with inhaled beclomethasone or budesonide are likely to improve lung function and asthma symptoms more than high-dose inhaled corticosteroid therapy alone.1 However, the first conclusion is based on data taken from an abstract2 and a package insert from Merck,3 while the second conclusion relies on data from another abstract.4

While it is hoped that the data Wenzel relies on for her conclusions and subsequent recommendations regarding use of these expensive drugs are sound, would it have been more prudent to wait until after these data are published following full peer review to ensure that they are valid? Given the high cost of these agents and the paucity of long-term efficacy and safety data in large populations of patients with asthma, I believe that even more caution should be exercised before making treatment recommendations . . . [Full Text of this Article]







HOME | CURRENT ISSUE | PAST ISSUES | TOPIC COLLECTIONS | CME | SUBMIT | SUBSCRIBE | HELP
CONDITIONS OF USE | PRIVACY POLICY | CONTACT US | SITE MAP
 
© 1999 American Medical Association. All Rights Reserved.