This Article  • Full text  • PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on ISI (16)  • Contact me when this article is cited  Related Content  • Related article  • Similar articles in JAMA  Topic Collections  • Patient Education/ Health Literacy  • Alert me on articles by topic

Jack E. Ansell, MD

JAMA. 1999;281:182-183.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Oral anticoagulation management has undergone a number of improvements since the discovery and first clinical use of dicumarol in the early 1940s. In this issue of THE JOURNAL, Sawicki¹ describes a model of anticoagulation management that introduces the next phase in this evolution, a model of patient self-management made possible by point-of-care PT monitoring.

Since the introduction of point-of-care PT instruments more than 10 years ago,² a number of instruments have become available or are in development that determine a PT-INR measurement equivalent by activating capillary whole blood with tissue thromboplastin. The end point of clotting is determined by assessing the movement of blood cells or oscillating iron particles or by assessing the generation of thrombin by a fluorescent probe. Instruments are small, lightweight and portable, and studies have confirmed that patients can easily and accurately perform a fingerstick and obtain a PT-INR measurement from a . . . [Full Text of this Article]

Author Affiliation: Department of Medicine, Boston University Medical Center, Boston, Mass.

RELATED ARTICLE

A Structured Teaching and Self-management Program for Patients Receiving Oral Anticoagulation: A Randomized Controlled Trial
Peter T. Sawicki and for the Working Group for the Study of Patient Self-Management of Oral Anticoagulation
JAMA. 1999;281(2):145-150.
ABSTRACT | FULL TEXT  

THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Anticoagulation or antiplatelet therapy of bioprosthetic heart valves recipients: an unresolved issue
Colli et al.
Eur. J. Cardiothorac. Surg. 2007;31:573-577.
ABSTRACT | FULL TEXT  

Anticoagulation Monitoring Part 1: Warfarin and Parenteral Direct Thrombin Inhibitors
Spinler et al.
The Annals of Pharmacotherapy 2005;39:1049-1055.
ABSTRACT | FULL TEXT  

Current and emerging treatment options for venous thrombosis: A case discussion
Haines and Nutescu
Am J Health Syst Pharm 2005;62:593-605.
FULL TEXT  

Comparing Self-Management of Oral Anticoagulant Therapy with Clinic Management: A Randomized Trial
Menendez-Jandula et al.
ANN INTERN MED 2005;142:1-10.
ABSTRACT | FULL TEXT  

Comparison of the Quality of Oral Anticoagulant Therapy Through Patient Self-management and Management by Specialized Anticoagulation Clinics in the Netherlands: A Randomized Clinical Trial
Gadisseur et al.
Arch Intern Med 2003;163:2639-2646.
ABSTRACT | FULL TEXT  

Anticoagulation in patients with thromboembolic disease
Tait
Thorax 2001;56:ii30-37.
FULL TEXT