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Medical, Legal, and Societal Implications of Androstenedione Use
Charles E. Yesalis III, MPH, ScD
JAMA. 1999;281:2043-2044.
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Use of the dietary supplement and androgenic steroid hormone androstenedione1 presents a number of questions and challenges. Is it a supplement or a drug? Should youngsters be allowed to use it? Should it be sold over-the-counter? Does it work as advertised? Is it safe?
During the past year, the public was exposed to a barrage of drug scandals in sports. These involved Olympic champions in track and field, swimming, and snowboarding, as well as elite cyclists, a 3-time winner of the Boston Marathon, and a professional tennis player.2 However, of all the drug-related stories in 1998, none received more media attention than home run record holder Mark McGwire's admission that he used androstenedione as a performance-enhancing substance.3
When questioned, supporters of McGwire borrowed several pages from today's political playbook and argued that what McGwire did was not illegal, was a personal matter, and, besides, . . . [Full Text of this Article]
Author Affiliation: Departments of Health Policy and Administration and Kinesiology, Pennsylvania State University, University Park.
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