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Charles E. Yesalis III, MPH, ScD

JAMA. 1999;281:2043-2044.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Use of the dietary supplement and androgenic steroid hormone androstenedione¹ presents a number of questions and challenges. Is it a supplement or a drug? Should youngsters be allowed to use it? Should it be sold over-the-counter? Does it work as advertised? Is it safe?

During the past year, the public was exposed to a barrage of drug scandals in sports. These involved Olympic champions in track and field, swimming, and snowboarding, as well as elite cyclists, a 3-time winner of the Boston Marathon, and a professional tennis player.² However, of all the drug-related stories in 1998, none received more media attention than home run record holder Mark McGwire's admission that he used androstenedione as a performance-enhancing substance.³

When questioned, supporters of McGwire borrowed several pages from today's political playbook and argued that what McGwire did was not illegal, was a personal matter, and, besides, . . . [Full Text of this Article]

Author Affiliation: Departments of Health Policy and Administration and Kinesiology, Pennsylvania State University, University Park.

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