 |
|
Stress-Induced Immunomodulation
Implications for Infectious Diseases?
Ronald Glaser, PhD;
Bruce Rabin, MD, PhD;
Margaret Chesney, PhD;
Sheldon Cohen, PhD;
Benjamin Natelson, MD
JAMA. 1999;281:2268-2270.
|
|
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
|
|
INTRODUCTION
There is now significant literature showing that psychological stress can down-regulate various aspects of the cellular immune response. It is also established that communication between the central nervous system and the immune system occurs through bidirectional signals linking the nervous, endocrine, and immune systems. Psychological stressors affect the immune system by disrupting these networks. In this overview, we discuss the implications of psychological stress-associated immune modulation and risk for infectious disease.
Stress and Immune Function
At a molecular level, human immune function is mediated by the release of cytokines, nonantibody messenger molecules, from a variety of cells of the immune system, and from other cells, such as endothelial cells. We will not be discussing cytokine production by nonimmune cells since they are not known to be related to the etiology or pathogenesis of immune-mediated disease.
These cytokines subsequently . . . [Full Text of this Article]
Stress and Infection-Related Antigens
Stress and Human Immunodeficiency Virus
New Directions for Study
Author Affiliations: Department of Medical Microbiology and Immunology, Ohio State University Medical Center, Columbus (Dr Glaser); Pathology Department, University of Pittsburgh Medical Center, Clinical Immunopathology-CLSI, Pittsburgh, Pa (Dr Rabin); Department of Medicine, University of California, San Francisco (Dr Chesney); Department of Psychology, Carnegie-Mellon University, Pittsburgh (Dr Cohen); and Department of Neurosciences, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, East Orange (Dr Natelson).
 CiteULike  Connotea  Del.icio.us  Digg  Reddit  Technorati  Twitter
What's this?
RELATED LETTER
Stress-Induced Immunomodulation
Mark Petticrew, Duncan Hunter, Ronald Glaser, Bruce Rabin, Margaret Chesney, Sheldon Cohen, and Benjamin Natelson
JAMA. 1999;282(23):2209-2210.
EXTRACT
| FULL TEXT
RELATED ARTICLE
June 23/30, 1999
JAMA. 1999;281(24):2403-2404.
EXTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
|
Coping as a Multisystem Construct Associated With Pathways Mediating HIV-Relevant Immune Function and Disease Progression
Temoshok et al.
Psychosom. Med. 2008;70:555-561.
ABSTRACT
| FULL TEXT
Promoting Health and Well-being in Lives of People Living with HIV and AIDS
Biswas
Psychology Developing Societies 2007;19:215-247.
ABSTRACT
Psychological Distress is Associated With Decreased Memory Helper T-cell and B-cell Counts in Pre-AIDS HIV Seropositive Men and Women but Only in Those With Low Viral Load
Motivala et al.
Psychosom. Med. 2003;65:627-635.
ABSTRACT
| FULL TEXT
Role of Psychosocial and Nutritional Stress on Poor Pregnancy Outcome
Hobel and Culhane
J. Nutr. 2003;133:1709S-1717.
ABSTRACT
| FULL TEXT
Effect of a Multivitamin and Mineral Supplement on Infection and Quality of Life: A Randomized, Double-Blind, Placebo-Controlled Trial
Barringer et al.
ANN INTERN MED 2003;138:365-371.
ABSTRACT
| FULL TEXT
Connecting the Dots Linking Mind, Behavior, and Disease: The Biological Concomitants of Coping Patterns: Commentary on "Attachment and Cancer: A Conceptual Integration"
Temoshok
Integr Cancer Ther 2002;1:387-391.
{micro}-Opioid Receptor Mediates Chronic Restraint Stress-Induced Lymphocyte Apoptosis
Wang et al.
J. Immunol. 2002;169:3630-3636.
ABSTRACT
| FULL TEXT
Depressive and Anxiety Disorders in Women With HIV Infection
Morrison et al.
Am. J. Psychiatry 2002;159:789-796.
ABSTRACT
| FULL TEXT
Intake of Wine, Beer, and Spirits and the Risk of Clinical Common Cold
Takkouche et al.
Am J Epidemiol 2002;155:853-858.
ABSTRACT
| FULL TEXT
Commentary: Peptic ulcer and its discontents
Levenstein
Int J Epidemiol 2002;31:29-33.
FULL TEXT
Evidence for a Shift in the Th-1 to Th-2 Cytokine Response Associated With Chronic Stress and Aging
Glaser et al.
Journals of Gerontology Series A: Biological Sciences and Medical Sciences 2001;56:M477-482.
ABSTRACT
| FULL TEXT
Pain and Immunologic Response to Root Canal Treatment and Subsequent Health Outcomes
Logan et al.
Psychosom. Med. 2001;63:453-462.
ABSTRACT
| FULL TEXT
Normal Responses to Injury Prevent Systemic Inflammation and Can Be Immunosuppressive
MUNFORD and PUGIN
Am. J. Respir. Crit. Care Med. 2001;163:316-321.
FULL TEXT
Stress-Induced Immunomodulation
Petticrew et al.
JAMA 1999;282:2209-2210.
FULL TEXT
|
