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  Vol. 281 No. 24, June 23, 1999 TABLE OF CONTENTS
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Clinical Crossroads: A 45-Year-Old Woman With Premenstrual Dysphoric Disorder

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: In her Clinical Crossroads article, Dr Parry1 neglected 2 points. First, Thys-Jacobs et al2 reported that economical calcium supplementation (Tums E-X) reduced core premenstrual syndrome symptoms of negative affect by 48% in 466 patients. Neither the history nor discussion by Parry shed more light on this possible dietary variable and its interplay with this complex neurohormonal scenario.3 If the patient is now "kindling," this supplement could have been appropriate and, possibly, protective 2 to 3 years ago.

Second and of more concern is that St John's wort, a medicine used widely in Europe, was perhaps misrepresented. The National Institutes of Health are redundantly validating the experiences of clinicians.4 St John's wort was referred to by the consultant as a dangerous, "ineffective" agent because of "MAO [monoamine oxidase] inhibitor" action.1 The source of this information about Hypericum perforatum (Greek, "to overcome an apparition") is unreferenced and perhaps overlooks . . . [Full Text of this Article]



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A 45-Year-Old Woman With Premenstrual Dysphoric Disorder
Barbara L. Parry
JAMA. 1999;281(4):368-373.
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A Structured Teaching and Self-management Program for Patients Receiving Oral Anticoagulation: A Randomized Controlled Trial
Peter T. Sawicki and for the Working Group for the Study of Patient Self-Management of Oral Anticoagulation
JAMA. 1999;281(2):145-150.
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