 |
 |

Lyme Disease Serology
Problems and Opportunities
Gary P. Wormser, MD;
Maria E. Aguero-Rosenfeld, MD;
Robert B. Nadelman, MD
JAMA. 1999;282:79-80.
 |
 |
| Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings. |
|
 |
 |
Serologic assays for Lyme disease, first used in 1983,1 are widely ordered in the United States, with an estimated 2.8 million tests performed annually.2 High demand undoubtedly has provided a potent stimulus for the development and marketing of a large number of assays for detection of antibody to Borrelia burgdorferi. As reported by Brown and colleagues3 of the Food and Drug Administration (FDA) in this issue of THE JOURNAL, 45 first-step assays, including enzyme-linked immunosorbent assays (ELISAs), immunofluorescent assays (IFAs), or immunodot techniques, and 8 second-step (supplemental) immunoblot assays have been granted FDA approval. Given the tremendous interest in these tests, it is important for physicians, other health care professionals, and the public to appreciate the strengths and limitations of these tests so that they are used in a helpful way. Brown and colleagues have addressed many of . . . [Full Text of this Article]
Author Affiliations: Division of Infectious Diseases (Drs Wormser and Nadelman) and the Departments of Medicine and Pathology (Dr Aguero-Rosenfeld), New York Medical College, Valhalla.
CiteULike Connotea Del.icio.us Digg Reddit Technorati Twitter
What's this?
RELATED ARTICLE
Role of Serology in the Diagnosis of Lyme Disease
S. Lori Brown, Sharon L. Hansen, and John J. Langone
JAMA. 1999;282(1):62-66.
ABSTRACT
| FULL TEXT
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES
Diagnosis of Lyme Borreliosis
Aguero-Rosenfeld et al.
Clin. Microbiol. Rev. 2005;18:484-509.
ABSTRACT
| FULL TEXT
Laboratory Testing for Lyme Disease: Possibilities and Practicalities
Reed
J. Clin. Microbiol. 2002;40:319-324.
FULL TEXT
Lyme borreliosis in Ontario: determining the risks
CMAJ 2000;162:1573-1574.
Borrelia burgdorferi B31 Erp Proteins That Are Dominant Immunoblot Antigens of Animals Infected with Isolate B31 Are Recognized by Only a Subset of Human Lyme Disease Patient Sera
Miller et al.
J. Clin. Microbiol. 2000;38:1569-1574.
ABSTRACT
| FULL TEXT
|