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To the Editor: Olestra, the Food and Drug Administration (FDA)–approved fat substitute contained in snack foods, lists an unspecified amount of vitamin K as an additive.^1-2 This raises concern because patients taking warfarin are typically educated about the need to maintain a consistent intake of foods containing vitamin K. Thus, vitamin K found in this unexpected source warrants further assessment.

Vitamin K has been added to these snack foods because olestra inhibits absorption of fat-soluble vitamins when taken concomitantly.¹ Eighty micrograms, 1 recommended daily intake (RDI) unit, of vitamin K has been added to each 1-oz serving of snack foods containing olestra to offset the dietary vitamin K that partitions into olestra.¹ This amount of vitamin K was determined in 2 trials in which healthy subjects were given 0, 8, 20, or 32 g of olestra daily for 8 weeks in the form of snack products.^3-4 Serum vitamin K levels . . . [Full Text of this Article]

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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

Authors' Financial Relationships With the Food and Beverage Industry and Their Published Positions on the Fat Substitute Olestra
Levine et al.
AJPH 2003;93:664-669.
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