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  Vol. 282 No. 13, October 6, 1999 TABLE OF CONTENTS
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Warning on Dietary Supplements

JAMA. 1999;282:1218.

Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

The FDA has issued a warning about a group of products—sold as "party drugs" or dietary supplements for body building, weight loss, and sleep inducement—that pose a significant hazard to public health. The products, sold under such names as GHB, Renewtrient, Revivarant, Blue Nitro, Firewater, and Serenity, are chemically related to {gamma}-butyrolactone (GBL), {gamma}-hydroxybutyric acid (GHB), and 1,4 butanediol (BD). They can cause dangerously low respiratory rates, unconsciousness or coma, vomiting, seizures, bradycardia, and death.

{gamma}-Butyrolactone, GHB, and BD have been linked to at least 145 serious illnesses that have been reported to the FDA, including eight deaths. These agents are powerful hypnotic substances that can produce severe and potentially dangerous sedative effects and increase the effects of alcohol; they are particularly dangerous when consumed with other central nervous system–depressant drugs. Legally available in the United States only for investigational purposes, GHB has been implicated as a "date rape" drug.

. . . [Full Text of this Article]



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THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES

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ABSTRACT | FULL TEXT  





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