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Joan Stephenson

JAMA. 1999;282:1317-1318.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

Baltimore—A new study by researchers at the National Institute of Allergy and Infectious Diseases (NIAID) has dealt the latest in a series of blows to the hope that it might be possible to eradicate HIV in patients treated with potent combinations of drugs known as highly active antiretroviral therapy (HAART). The group's findings, reported by NIAID director Anthony J. Fauci, MD, showed that patients whose blood (and in some cases lymph nodes) had no viable HIV after they received HAART and another drug aimed at purging hidden reservoirs of latent virus experienced a swift resurgence of HIV when they discontinued therapy.

Because HAART (a regimen that generally involves a protease inhibitor and two other antiretroviral drugs) can reduce HIV in the plasma to undetectable levels in some patients, scientists had proposed that long-term treatment with these regimens had the potential to eventually eradicate the virus (JAMA. . . [Full Text of this Article]