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To the Editor: The Seychelles Child Development Study is a longitudinal study of the effects of prenatal and postnatal exposure to methylmercury from fish consumption on children's development.¹ A cohort of 740 mother-infant pairs was enrolled at 6 months of age and examined with age-appropriate developmental tests at 6, 19, 29, and 66 months. Exposure was measured with total mercury concentration in maternal hair during pregnancy and in children's hair at 66 months. Associations between prenatal and postnatal (66-month analyses only) exposure and developmental outcomes were examined with multiple regression analyses, adjusted for covariates. No adverse effects have been found through the 66-month evaluations.¹

Following publication of the 66-month data, the National Institute of Environmental Health Sciences sponsored a workshop (November 18-20, 1998) on the assessment of health effects from exposure to methylmercury. During the workshop, expert reviewers questioned whether including both prenatal and postnatal exposure indices in the same . . . [Full Text of this Article]

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Commentary: Mercury, PCB, and now eicosapentaenoic acid: still another reason why pregnant women should be concerned about eating seafood?
Olsen
Int J Epidemiol 2001;30:1279-1280.
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