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Adding to the Armamentarium for Influenza Control

Gregory A. Poland, MD; Robert Couch, MD

JAMA. 1999;282:182-184.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

In the United States, national influenza vaccine recommendations have typically been based on the prevention of complications and death among high-risk persons. More recent is the increasing awareness that above and beyond the more severe individual medical consequences of influenza, enormous societal economic costs are associated with disruptions due to school and work absences and days of illness. In this issue of THE JOURNAL, Nichol et al¹ report that use of a live, attenuated influenza virus (LAIV) vaccine, administered by intranasal spray to healthy, working adults (a group without a routine recommendation to receive influenza vaccine), was followed in the subsequent influenza epidemic season by a significant reduction in severe febrile illness, days lost from work, health care visits, and the medication use that accompanies these illnesses. Are these findings important? From an individual, medical, and public health point of view, the answer . . . [Full Text of this Article]

Author Affiliations: Clinical Pharmacology and Mayo Vaccine Research Group, Mayo Medical School and Foundation, Rochester, Minn (Dr Poland); and Department of Microbiology and Immunology, Baylor College of Medicine, Houston, Tex (Dr Couch).

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