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Joan Stephenson, PhD

JAMA. 1999;282:226.

	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

A plan by the National Cancer Institute (NCI) to restructure its clinical trials system is under way and is expected to dramatically change the way NCI-funded multicenter trials are proposed, reviewed, and coordinated.

Under the new system, for example, proposals for clinical trials, traditionally the turf of the NCI's Clinical Trial Cooperative Groups, will be drawn from a variety of sources, including clinical and basic scientists from academia and industry, patient advocacy groups, and others. Each proposal will also be judged competitively through a new peer review process involving a disease-specific Concept Evaluation Panel, two thirds of whose members come from outside the NCI.

Other major elements of the plan include a national network of physician participants aimed at increasing access of physicians and patients who wish to participate in clinical trials.

To obtain a booklet about the new system, Clinical Trials: A Blueprint for the Future. . . [Full Text of this Article]

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