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	Since this article does not have an abstract, we have provided the first 150 words of the full text and any section headings.

To the Editor: In their study evaluating the weight-loss potential of (-)hydroxycitric acid (HCA) derived from Garcinia cambogia, Dr Heymsfield and colleagues¹ cite our HCA work. We wish to give a counterpoint to the conclusion expressed by the authors.

Based on their single clinical study, Heymsfield et al state that "These observations ... do not support a role as currently prescribed for the widely used herb G cambogia as a facilitator of weight loss." Aside from this strong statement, which contradicts the positive results reported in several earlier HCA clinical studies, the design of the trial indicates that the authors took little advantage of previously reported experiences involving HCA.^2-4 In their own preclinical research, they report a prerequisite that suggests for HCA to effectively inhibit fat formation and body weight it needs to be administered with a simple carbohydrate-rich (lipogenic) diet.⁵

The study in question⁵ coadministered HCA with a high-fiber . . . [Full Text of this Article]

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RELATED ARTICLE

Garcinia cambogia (Hydroxycitric Acid) as a Potential Antiobesity Agent: A Randomized Controlled Trial
Steven B. Heymsfield, David B. Allison, Joseph R. Vasselli, Angelo Pietrobelli, Debra Greenfield, and Christopher Nunez
JAMA. 1998;280(18):1596-1600.
ABSTRACT | FULL TEXT  

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